Of the multiple unique stromal cell types common to solid tumors, tumor-associated
macrophages (TAMs) are significant for fostering tumor progression. The protumor properties of …

The classic view that the role of immune cells in cancer is primarily one of tumor rejection
has been supplanted by a more complex view of leukocytes having both pro- and anti-tumor …

Glutathione peroxidase (GSHPx) is an important selenium‐containing enzyme which protects
cells from peroxide damage and also has a role in leukotriene formation. We report the …

Germline mutation analysis was performed in 469 VHL families from North America, Europe,
and Japan. Germline mutations were identified in 300/469 (63%) of the families tested; 137 …

Background The dissection of complex traits of economic importance to the pig industry
requires the availability of a significant number of genetic markers, such as single nucleotide …

… PDSC5 tumor cells were injected sc into FcRg+/À and FcRgÀ/À syngeneic FVB/n mice.
Titers of IgG in serum of wild-type (WT) FVB/n versus transplanted FVB/n mice evaluated by …

… mutations were detected including missense (n = 19), nonsense (n = 6), frameshift deletions
or insertions (n = 12), in frame deletions (n = 2) and a splice donor site mutation (n = 1). The …

… pancreatic ductal adenocarcinoma (AdenoCa; n = 33), IPMN (n = 5), and islet cell carcinomas
(Islet Cell Ca; n = 6), as compared with healthy pancreas tissue (n = 17) assessed by …

The use of genome wide single nucleotide polymorphism (SNP) arrays for high resolution
molecular cytogenetic analysis using a combination of quantitative and genotype analysis is …

Loss of heterozygosity (LOH) studies have suggested that somatic mutations of a tumour
suppressor gene or genes on chromosome 3p are a critical event In the pathogenesls of non-…