Vitamin D as an anti-microbial and anti-inflammatory therapy for Cystic Fibrosis

K Herscovitch, N Dauletbaev, LC Lands - Paediatric respiratory reviews, 2014 - Elsevier
Cystic fibrosis (CF) is characterized by chronic infection and inflammation in the airways that
lead to progressive lung damage and early death. Current anti-inflammatory therapies are …

[HTML][HTML] Update in chronic obstructive pulmonary disease 2019

P Alter, JR Baker, N Dauletbaev… - American Journal of …, 2020 - atsjournals.org
… Marchetti N. Anabolic medications for muscle wasting in chronic obstructive pulmonary
disease: is the evidence getting stronger? Am J Respir Crit Care Med 2019;199:256–258. …

A scoping review of mHealth monitoring of pediatric bronchial asthma before and during COVID-19 pandemic

N Dauletbaev, ZS Oftring, W Akik… - Paediatric respiratory …, 2022 - Elsevier
Mobile (m) Health technology is well-suited for Remote Patient Monitoring (RPM) in a patient’s
habitual environment. In recent years there have been fast-paced developments in …

Prophylactic antibiotic therapy is associated with an increased prevalence of Aspergillus colonization in adult cystic fibrosis patients

J Bargon, N Dauletbaev, B Köhler, M Wolf… - Respiratory …, 1999 - Elsevier
Aspergillus colonization is a common phenomenon in adult cystic fibrosis (CF) patients. The
clinical significance of Aspergillus for the pathogenesis of CF lung disease remains unclear …

Down‐regulation of IL‐8 by high‐dose vitamin D is specific to hyperinflammatory macrophages and involves mechanisms beyond up‐regulation of DUSP1

N Dauletbaev, K Herscovitch, M Das… - British journal of …, 2015 - Wiley Online Library
Background and Purpose There is current interest in vitamin D as a potential anti‐inflammatory
treatment for chronic inflammatory lung disease, including cystic fibrosis ( CF ). Vitamin D …

Stimulation of the RIG-I/MAVS pathway by polyinosinic: polycytidylic acid upregulates IFN-β in airway epithelial cells with minimal costimulation of IL-8

N Dauletbaev, M Cammisano… - The Journal of …, 2015 - journals.aai.org
Pharmacological stimulation of the antiviral cytokine IFN-β in the airways may help to
counter deleterious virus-induced exacerbations in chronic inflammatory lung diseases (asthma, …

Combined effect of dietary supplementation with pressurized whey and exercise training in chronic obstructive pulmonary disease: a randomized, controlled, double …

L Laviolette, LC Lands, N Dauletbaev… - Journal of medicinal …, 2010 - liebertpub.com
… Two patients randomized in the whey group completed only the supplementation phase
because of pneumonia (n = 1) and refusal to participate in the exercise training program (n = 1). …

Whey protein hydrolysates decrease IL-8 secretion in lipopolysaccharide (LPS)-stimulated respiratory epithelial cells by affecting LPS binding to Toll-like receptor 4

…, N Dauletbaev, S Kubow, N Mawji… - British Journal of …, 2013 - cambridge.org
Whey proteins (WP) exert anti-inflammatory and antioxidant effects. Hyperbaric pressurisation
of whey increases its digestibility and changes the spectrum of peptides released during …

[HTML][HTML] A phase II study on safety and efficacy of high-dose N-acetylcysteine in patients with cystic fibrosis

N Dauletbaev, P Fischer, B Aulbach, J Gross… - European journal of …, 2009 - Springer
Objective We conducted a single-centre, randomised, double-blinded, placebo-controlled
phase II clinical study to test safety and efficacy of a 12-week therapy with low-dose (700 mg/…

Ibuprofen modulates NF-ĸB activity but not IL-8 production in cystic fibrosis respiratory epithelial cells

N Dauletbaev, J Lam, D Eklove, M Iskandar, LC Lands - Respiration, 2010 - karger.com
Background: High-dose ibuprofen is clinically effective in cystic fibrosis (CF); however, its
molecular mechanisms are poorly understood. Objective: To test the hypothesis that clinically …