Elevated concentrations of albumin in the urine, albuminuria, are a hallmark of diabetic
kidney disease and are associated with an increased risk for end-stage renal disease and …

Increased levels of the urinary albumin-to-creatinine ratio (UACR) are associated with higher
risk of kidney disease progression and cardiovascular events, but underlying mechanisms …

Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated
with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the …

Estimated glomerular filtration rate (eGFR) reflects kidney function. Progressive eGFR-decline
can lead to kidney failure, necessitating dialysis or transplantation. Hundreds of loci from …

Introduction: Diabetes-associated kidney disease is characterized by impairment of renal
function and albuminuria. The aim of the present study was to assess whether sleep-…

Introduction Patients with diabetes mellitus type 2 (DM2) are at high risk for micro- and
macrovascular disease. Here, we explore the degree of traditional risk factor control in the …

The reduction of micro-and macrovascular end points in patients with diabetes mellitus type
2 is achieved by control of traditional risk factors such as hyperglycemia, hyperlipidemia, …

Background: Diabetes-related nephropathy (DN) is characterized by decreasing glomerular
filtration rate (eGFR) and increasing urine albumin-to-creatinine ratio (UACR). Sleep-…

Methods: DIACORE is a prospective two-center cohort study with extensive, standardized
phenotyping and 2-yearly follow-ups. Inclusion criteria: DM 2, Caucasian, age>= 18yrs. Key …

Percutaneous liver biopsy performed early in the intensive care unit: key to an optimized organ
allocation? Percutaneous liver biopsy performed early in the intensive care unit: key to an …