Increased Macrolide Resistance of Mycoplasma pneumoniae in Pediatric Patients with Community-Acquired Pneumonia

M Morozumi, S Iwata, K Hasegawa… - Antimicrobial agents …, 2008 - Am Soc Microbiol
Among 380 Mycoplasma pneumoniae isolates from 3,678 pediatric patients with community-acquired
pneumonia, 50 macrolide-resistant strains had an A2063G transition in domain V …

Macrolide-resistant Mycoplasma pneumoniae: characteristics of isolates and clinical aspects of community-acquired pneumonia

M Morozumi, T Takahashi, K Ubukata - Journal of Infection and …, 2010 - Springer
Mycoplasma pneumoniae is one of the main pathogens causing community-acquired
respiratory tract infections in children and adults. Macrolide (ML) antibiotics are recognized …

Rapid Effectiveness of Minocycline or Doxycycline Against Macrolide-Resistant Mycoplasma pneumoniae Infection in a 2011 Outbreak Among Japanese Children

T Okada, M Morozumi, T Tajima… - Clinical infectious …, 2012 - academic.oup.com
Background. Mycoplasma pneumoniae is a major pathogen causing community-acquired
pneumonia in children and young adults. Outbreaks typically occur at intervals of several years…

Emergence of Macrolide-Resistant Mycoplasma pneumoniae with a 23S rRNA Gene Mutation

M Morozumi, K Hasegawa, R Kobayashi… - Antimicrobial agents …, 2005 - Am Soc Microbiol
A total of 195 Mycoplasma pneumoniae strains were isolated from 2,462 clinical specimens
collected between April 2002 and March 2004 from pediatric outpatients with respiratory …

Comprehensive detection of causative pathogens using real-time PCR to diagnose pediatric community-acquired pneumonia

K Hamano-Hasegawa, M Morozumi… - Journal of Infection and …, 2008 - Elsevier
We have developed a real-time reverse transcription-PCR (RT-PCR) method to detect 13
respiratory viruses: influenza virus A and B; respiratory syncytial virus (RSV) subgroup A and B…

A comparative clinical study of macrolide-sensitive and macrolide-resistant Mycoplasma pneumoniae infections in pediatric patients

…, O Komiyama, S Iwata, M Morozumi… - Journal of infection and …, 2009 - Elsevier
In recent years, the increased prevalence of macrolide-resistant Mycoplasma pneumoniae (MR-M.
pneumoniae) has become a significant issue in Japan. We isolated 94 strains of M. …

[HTML][HTML] Effects of pneumococcal conjugate vaccine on genotypic penicillin resistance and serotype changes, Japan, 2010–2017

K Ubukata, M Takata, M Morozumi… - Emerging infectious …, 2018 - ncbi.nlm.nih.gov
To clarify year-to-year changes in capsular serotypes, resistance genotypes, and multilocus
sequence types of Streptococcus pneumoniae, we compared isolates collected from …

[HTML][HTML] Changes in capsule and drug resistance of pneumococci after introduction of PCV7, Japan, 2010–2013

N Chiba, M Morozumi, M Shouji, T Wajima… - Emerging Infectious …, 2014 - ncbi.nlm.nih.gov
We aimed to clarify changes in serotypes and genotypes mediating β-lactam and macrolide
resistance in Streptococcus pneumoniae isolates from Japanese children who had invasive …

Rapid detection of eight causative pathogens for the diagnosis of bacterial meningitis by real-time PCR

N Chiba, SY Murayama, M Morozumi… - Journal of Infection and …, 2009 - Springer
We aimed to detect causative pathogens in cerebrospinal fluid (CSF) collected from patients
diagnosed with bacterial meningitis by real-time polymerase chain reaction (PCR). In …

Simultaneous detection of pathogens in clinical samples from patients with community-acquired pneumonia by real-time PCR with pathogen-specific molecular …

M Morozumi, E Nakayama, S Iwata, Y Aoki… - Journal of clinical …, 2006 - Am Soc Microbiol
In this study, real-time PCR with pathogen-specific molecular beacons (MB) and primers
was evaluated for prediction of community-acquired pneumonia (CAP) causative agents, …