User profiles for Mika Kähönen
Kähönen Mikaprofessor of clinical physiology, Tampere University Verified email at tuni.fi Cited by 87145 |
Haptoglobin 2 allele associates with unstable carotid plaque and major cardiovascular events
…, J Tuimala, M Jauhiainen, A Jula, M Kähönen… - Atherosclerosis, 2013 - Elsevier
Objective Intraplaque hemorrhages (IPH) may predispose to unstable atherosclerotic disease
and its atherothrombotic complications, ischemic stroke and coronary syndromes. However…
and its atherothrombotic complications, ischemic stroke and coronary syndromes. However…
Computationally estimated apolipoproteins B and A1 in predicting cardiovascular risk
OBJECTIVE: Apolipoproteins B (apoB) and A1 (apoA1) may be better markers of atherosclerosis
than serum lipids. We used computational methods to estimate apoB and apoA1 from …
than serum lipids. We used computational methods to estimate apoB and apoA1 from …
[HTML][HTML] Comprehensive inherited risk estimation for risk-based breast cancer screening in women
…, J Kettunen, A Mannermaa, K Aalto-Setälä, M Kähönen… - NaN, 2024 - citedrive.com
PURPOSE Family history (FH) and pathogenic variants (PVs) are used for guiding risk
surveillance in selected high-risk women but little is known about their impact for breast cancer …
surveillance in selected high-risk women but little is known about their impact for breast cancer …
Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts
Background— High-throughput profiling of circulating metabolites may improve cardiovascular
risk prediction over established risk factors. Methods and Results— We applied …
risk prediction over established risk factors. Methods and Results— We applied …
[HTML][HTML] Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA
Genome-wide association studies have identified numerous loci linked with complex diseases,
for which the molecular mechanisms remain largely unclear. Comprehensive molecular …
for which the molecular mechanisms remain largely unclear. Comprehensive molecular …
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
…, KB Jacobs, JO Jansson, A Jula, M Kähönen… - Nature …, 2013 - nature.com
Approaches exploiting trait distribution extremes may be used to identify loci associated
with common traits, but it is unknown whether these loci are generalizable to the broader …
with common traits, but it is unknown whether these loci are generalizable to the broader …
A catalog of genetic loci associated with kidney function from analyses of a million individuals
Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic
complications. Through trans-ancestry meta-analysis of genome-wide association studies of …
complications. Through trans-ancestry meta-analysis of genome-wide association studies of …
Genome-wide association study identifies multiple loci influencing human serum metabolite levels
Nuclear magnetic resonance assays allow for measurement of a wide range of metabolic
phenotypes. We report here the results of a GWAS on 8,330 Finnish individuals genotyped and …
phenotypes. We report here the results of a GWAS on 8,330 Finnish individuals genotyped and …
High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism
…, T Tynkkynen, R Laatikainen, MR Järvelin, M Kähönen… - Analyst, 2009 - pubs.rsc.org
A high-throughput proton (1H) nuclear magnetic resonance (NMR) metabonomics approach
is introduced to characterise systemic metabolic phenotypes. The methodology combines …
is introduced to characterise systemic metabolic phenotypes. The methodology combines …
Branched-chain and aromatic amino acids are predictors of insulin resistance in young adults
…, T Rönnemaa, T Lehtimäki, M Kähönen… - Diabetes …, 2013 - Am Diabetes Assoc
OBJECTIVE Branched-chain and aromatic amino acids are associated with the risk for future
type 2 diabetes; however, the underlying mechanisms remain elusive. We tested whether …
type 2 diabetes; however, the underlying mechanisms remain elusive. We tested whether …