Comprehensive genomic profiles of small cell lung cancer

…, GM Wright, PA Russell, B Solomon, I Koch, M Lindner… - Nature, 2015 - nature.com
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest
human cancers. In nearly all the tumours analysed we found bi-allelic inactivation of TP53 …

[HTML][HTML] Transfer entropy—a model-free measure of effective connectivity for the neurosciences

R Vicente, M Wibral, M Lindner, G Pipa - Journal of computational …, 2011 - Springer
Understanding causal relationships, or effective connectivity, between parts of the brain is of
utmost importance because a large part of the brain’s activity is thought to be internally …

" Coherence radar" and" spectral radar"-new tools for dermatological diagnosis

G Häusler, MW Lindner - Journal of biomedical optics, 1998 - spiedigitallibrary.org
‘‘Coherence radar,’’an optical 3-D sensor based on short coherence interferometry, is used
to measure skin surface topology. This method is called optical coherence profilometry (OCP…

Dysfunctional long-range coordination of neural activity during Gestalt perception in schizophrenia

…, W Singer, C Haenschel, M Lindner… - Journal of …, 2006 - Soc Neuroscience
Recent theoretical and empirical research on schizophrenia converges on the notion that
core aspects of the pathophysiology of the disorder may arise from a dysfunction in the …

[HTML][HTML] Measuring information-transfer delays

…, V Priesemann, F Siebenhühner, H Seiwert, M Lindner… - PloS one, 2013 - journals.plos.org
In complex networks such as gene networks, traffic systems or brain circuits it is important to
understand how long it takes for the different parts of the network to effectively influence one …

[HTML][HTML] TRENTOOL: A Matlab open source toolbox to analyse information flow in time series data with transfer entropy

M Lindner, R Vicente, V Priesemann, M Wibral - BMC neuroscience, 2011 - Springer
Background Transfer entropy (TE) is a measure for the detection of directed interactions.
Transfer entropy is an information theoretic implementation of Wiener's principle of …

Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo

…, C Ota, R Costa, HB Schiller, M Lindner… - European …, 2017 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease with poor prognosis and
limited therapeutic options. The incidence of IPF increases with age, and ageing-related …

Transfer entropy in magnetoencephalographic data: quantifying information flow in cortical and cerebellar networks

M Wibral, B Rahm, M Rieder, M Lindner… - Progress in biophysics …, 2011 - Elsevier
The analysis of cortical and subcortical networks requires the identification of their nodes, and
of the topology and dynamics of their interactions. Exploratory tools for the identification of …

Protease-Mediated Release of Chemotherapeutics from Mesoporous Silica Nanoparticles to ex Vivo Human and Mouse Lung Tumors

…, DA Bölükbas, C Argyo, S Datz, M Lindner… - ACS …, 2015 - ACS Publications
Nanoparticles allow for controlled and targeted drug delivery to diseased tissues and therefore
bypass systemic side effects. Spatiotemporal control of drug release can be achieved by …

An ex vivo model to induce early fibrosis-like changes in human precision-cut lung slices

…, M Lehmann, M Lindner… - … of Physiology-Lung …, 2017 - journals.physiology.org
Idiopathic pulmonary fibrosis (IPF) is a devastating chronic interstitial lung disease (ILD)
characterized by lung tissue scarring and high morbidity. Lung epithelial injury, myofibroblast …