Systematic review of studies of the effect of hyperoxia on coronary blood flow

H Farquhar, M Weatherall, M Wijesinghe, K Perrin… - American heart …, 2009 - Elsevier
BACKGROUND: International guidelines recommend the routine use of oxygen in the initial
treatment of myocardial infarction, yet it is uncertain what effect this might have on …

Routine use of oxygen in the treatment of myocardial infarction: systematic review

M Wijesinghe, K Perrin, A Ranchord, M Simmonds… - Heart, 2009 - heart.bmj.com
Context: International guidelines recommend the routine use of oxygen therapy in the
treatment of myocardial infarction (MI). Objective: To undertake a systematic review and meta-…

[HTML][HTML] Honey in the treatment of burns: a systematic review and meta-analysis of its efficacy

M Wijesinghe, M Weatherall, K Perrin… - Database of Abstracts …, 2009 - ncbi.nlm.nih.gov
The authors concluded that available evidence indicated a greater efficacy of honey compared
with alternative dressing treatments for superficial or partial thickness burns. The authors' …

Randomised controlled trial of high concentration versus titrated oxygen therapy in severe exacerbations of asthma

K Perrin, M Wijesinghe, B Healy, K Wadsworth… - Thorax, 2011 - thorax.bmj.com
Background The effect on Paco 2 of high concentration oxygen therapy when administered
to patients with severe exacerbations of asthma is uncertain. Methods 106 patients with …

The effect of supplemental oxygen on hypercapnia in subjects with obesity-associated hypoventilation: a randomized, crossover, clinical study

M Wijesinghe, M Williams, K Perrin, M Weatherall… - Chest, 2011 - Elsevier
… Author contributions: Dr Wijesinghe had full access to all of the data in the study and
takes full responsibility for their integrity and the accuracy of the data analysis, including any …

Accuracy of patient self‐report as a measure of inhaled asthma medication use

…, K Perrin, A Pritchard, M Williams, M Wijesinghe… - …, 2013 - Wiley Online Library
Background and objective Measuring adherence to inhaled asthma treatment is a key
priority for asthma care. The aim of this study was to determine the relationship between self‐…

International trends in asthma mortality rates in the 5-to 34-year age group: a call for closer surveillance

M Wijesinghe, M Weatherall, K Perrin, J Crane… - Chest, 2009 - Elsevier
Background International time trends in asthma mortality have played an important sentinel
role in the identification of two epidemics of asthma mortality in some countries in the 1960s …

The value of the CRB65 score to predict mortality in exacerbations of COPD requiring hospital admission

L Edwards, K Perrin, M Wijesinghe, M Weatherall… - …, 2011 - Wiley Online Library
Background and Objective: The CRB65 score, a risk stratification method validated for use
in community‐acquired pneumonia, has recently been shown to have utility in acute …

Randomized controlled trial of high concentration oxygen in suspected community-acquired pneumonia

M Wijesinghe, K Perrin, B Healy… - Journal of the Royal …, 2012 - journals.sagepub.com
Objective To determine whether high concentration oxygen increases the PaCO 2 in the
treatment of community-acquired pneumonia. Design Randomized controlled clinical trial in …

Call for withdrawal of LABA single-therapy inhaler in asthma

R Beasley, K Perrin, M Weatherall, M Wijesinghe - The Lancet, 2010 - thelancet.com
Long-acting β agonists (LABAs) might increase the risk of asthma mortality when used by
patients with unstable asthma without concomitant inhaled corticosteroids or scheduled …