The Severe Respiratory Insufficiency (SRI) Questionnaire A specific measure of health-related quality of life in patients receiving home mechanical ventilation

…, K Freidel, B Schucher, H Baumann, M Wiebel… - Journal of clinical …, 2003 - Elsevier
Background and Objective: The objective of this study was to develop a specific instrument
for measuring health-related quality of life (HRQL) in patients receiving home mechanical …

Assessment of morphological MRI for pulmonary changes in cystic fibrosis (CF) patients: comparison to thin-section CT and chest x-ray

…, A Schmaehl, C Fink, C Plathow, M Wiebel… - Investigative …, 2007 - journals.lww.com
Objectives: As pulmonary complications are life limiting in patients with cystic fibrosis (CF),
repeated chest imaging [chest x-ray, computed tomography (CT)] is needed for follow up. With …

Proton MRI appearance of cystic fibrosis: comparison to CT

…, A Schmähl, C Fink, C Plathow, M Wiebel… - European …, 2007 - Springer
Cystic fibrosis (CF) is the most frequent inherited disorder leading to premature death in the
Caucasian population. As life expectancy is limited by pulmonary complications, repeated …

Pirfenidone in idiopathic pulmonary fibrosis: real-life experience from a German tertiary referral center for interstitial lung diseases

…, CP Heussel, PA Schnabel, M Puderbach, M Wiebel… - Respiration, 2014 - karger.com
Background: Pirfenidone is a novel antifibrotic drug for the treatment of mild-to-moderate
idiopathic pulmonary fibrosis (IPF). However, adverse events may offset treatment benefits and …

Automatic airway analysis on multidetector computed tomography in cystic fibrosis: correlation with pulmonary function testing

…, O Weinheimer, S Ley, MA Mall, M Wiebel… - Journal of thoracic …, 2013 - journals.lww.com
Purpose: To evaluate the fully automatic quantification of airway dimensions on chest
multidetector computed tomography (MDCT) performed in cystic fibrosis (CF) patients. Airflow …

Repaglinide versus insulin for newly diagnosed diabetes in patients with cystic fibrosis: a multicentre, open-label, randomised trial

…, U Mellies, HG Posselt, M Wiebel… - The Lancet Diabetes & …, 2018 - thelancet.com
Background As survival among patients with cystic fibrosis has improved in recent decades,
complications have become increasingly relevant. The most frequent complication is cystic-…

[HTML][HTML] Evaluation of health-related quality of life using the MOS 36-Item Short-Form Health Status Survey in patients receiving noninvasive positive pressure …

…, K Freidel, B Schucher, H Baumann, M Wiebel… - Intensive care …, 2003 - Springer
Objective To collect benchmark data on the MOS 36-Item Short-Form Health Status Survey (SF-36)
in patients receiving noninvasive positive pressure ventilation and to examine …

[HTML][HTML] Pulmonary emphysema in cystic fibrosis detected by densitometry on chest multidetector computed tomography

MO Wielpütz, O Weinheimer, M Eichinger, M Wiebel… - PloS one, 2013 - journals.plos.org
Background Histopathological studies on lung specimens from patients with cystic fibrosis (CF)
and recent results from a mouse model indicate that emphysema may contribute to CF …

[HTML][HTML] Optical coherence tomography detects structural abnormalitiesof the nasal mucosa in patients with cystic fibrosis

…, E Baroke, R Eberhardt, S Wege, M Wiebel… - Journal of Cystic …, 2016 - Elsevier
Background Chronic inflammation and remodeling of the airways remain a hallmark of cystic
fibrosis (CF). However, knowledge of the associated mucosal micro-anatomical changes is …

Exercise reduces airway sodium ion reabsorption in cystic fibrosis but not in exercise asthma

L Schmitt, M Wiebel, F Frese, C Dehnert… - European …, 2011 - Eur Respiratory Soc
When ventilating large volumes of air during exercise, airway fluid secretion is essential for
airway function. Since these are impaired in cystic fibrosis and exercise-induced asthma, it …