Recovery of neutrophil apoptosis by ectoine: a new strategy against lung inflammation

…, U Krämer, A Weissenberg, M Kroker… - European …, 2013 - Eur Respiratory Soc
The life span of neutrophilic granulocytes has a determining impact on the intensity and
duration of neutrophil driven lung inflammation. Based on the compatible solute ectoine, we …

[HTML][HTML] Carbon nanoparticles induce ceramide-and lipid raft-dependent signalling in lung epithelial cells: a target for a preventive strategy against environmentally …

…, I Felsner, D Stöckmann, S Jakob, M Kroker… - Particle and fibre …, 2012 - Springer
Background Particulate air pollution in lung epithelial cells induces pathogenic endpoints
like proliferation, apoptosis, and pro-inflammatory reactions. The activation of the epidermal …

[HTML][HTML] Preventing carbon nanoparticle-induced lung inflammation reduces antigen-specific sensitization and subsequent allergic reactions in a mouse model

M Kroker, U Sydlik, A Autengruber, C Cavelius… - Particle and fibre …, 2015 - Springer
Background Exposure of the airways to carbonaceous nanoparticles can contribute to the
development of immune diseases both via the aggravation of the allergic immune response in …

[HTML][HTML] The compatible solute ectoine reduces the exacerbating effect of environmental model particles on the immune response of the airways

K Unfried, M Kroker, A Autengruber, M Gotić… - Journal of allergy, 2014 - hindawi.com
Exposure of humans to particulate air pollution has been correlated with the incidence and
aggravation of allergic airway diseases. In predisposed individuals, inhalation of …

c-Src-mediated activation of Erk1/2 is a reaction of epithelial cells to carbon nanoparticle treatment and may be a target for a molecular preventive strategy

…, J Haendeler, N Büchner, D Stöckmann, M Kroker… - 2010 - degruyter.com
Owing to their specific physico/chemical properties, engineered as well as environmental
nanoparticles can induce pathogenic endpoints in humans. Earlier studies demonstrated that …

[HTML][HTML] Signalling-dependent adverse health effects of carbon nanoparticles are prevented by the compatible solute mannosylglycerate (firoin) in vitro and in vivo

A Autengruber, U Sydlik, M Kroker, T Hornstein… - PLoS …, 2014 - journals.plos.org
The inhalation of combustion-derived nanoparticles leads to adverse health effects in the
airways. In this context the induction of membrane-coupled signalling is considered as …

[PDF][PDF] Are private equity investors governance champions or simply stock picking specialists

M Kroker, MS Rapp, M Wolff - En ligne: http://www. efmaefm. org …, 2010 - efmaefm.org
There is an ongoing debate about the economic effects of private equity investors. Whereas
private equity investors often claim that they act as governance champions helping firms to …

Inhalation Of The Compatible Solute Ectoine Reduces Neutrophilic Lung Inflammation In Environmentally Exposed Individuals

K Unfried, U Kramer, U Sydlik, M Kroker… - B31 …, 2012 - atsjournals.org
METHODS: First, lung inflammation was induced in rats by intra-tracheal application of 2.5
mg/kg environmental carbon model particles. Lung inflammation as well as cell parameters of …

Lung Inflammation As A Major Cause Of Carbon Nanoparticle-Induced Adjuvant Activity

U Sydlik, M Kroker, H Weighardt… - A32. SMOKE-RELATED …, 2012 - atsjournals.org
Results: Results at the level of sensitization showed that CNP induced immediate airway
inflammation had immune adjuvant activity, resulted in an increase of specific cell populations …

Lung inflammation is significantly reduced by recovery of neutrophil apoptosis in vivo

K Unfried, U Sydlik, M Kroker, A Paunel-Görgülü… - 2012 - Eur Respiratory Soc
INTRODUCTION: Neutrophil apoptosis is considered to be a major regulator of neutrophil
driven lung inflammation. The compatible solute ectoine has been described to act preventive …