User profiles for Matthaios Speletas

Matthaios Speletas

University of Thessaly, Faculty of Medicine
Verified email at med.uth.gr
Cited by 4070

Genetics of hereditary angioedema revisited

AE Germenis, M Speletas - Clinical reviews in allergy & immunology, 2016 - Springer
Contemporary genetic research has provided evidences that angioedema represents a
diverse family of disorders related to kinin metabolism, with a much greater genetic complexity …

A novel mutation in TREM2 gene causing Nasu-Hakola disease and review of the literature

…, A Markou, D Papadimitriou, M Speletas… - Neurobiology of …, 2017 - Elsevier
Nasu-hakola disease (NHD) is a rare disease characterized by bone cysts and fractures,
frontal lobe syndrome, and progressive presenile dementia. NHD may be the prototype of …

International consensus on the use of genetics in the management of hereditary angioedema

…, MA Riedl, F Sheikh, S Peter, M Speletas… - The Journal of Allergy …, 2020 - Elsevier
Hereditary angioedema (HAE) is becoming much more genetically complex than was initially
considered. Thus, the role of HAE genetics is expanding beyond research laboratories, …

[HTML][HTML] Foxp3 expression in human cancer cells

V Karanikas, M Speletas, M Zamanakou… - Journal of translational …, 2008 - Springer
Objective Transcription factor forkhead box protein 3 (Foxp3) specifically characterizes the
thymically derived naturally occurring regulatory T cells (Tregs). Limited evidence indicates …

International consensus on the diagnosis and management of pediatric patients with hereditary angioedema with C1 inhibitor deficiency

…, P Schmid‐Grendelmeier, S Péter, M Speletas… - Allergy, 2017 - Wiley Online Library
Background The consensus documents published to date on hereditary angioedema with C1
inhibitor deficiency (C1‐ INH ‐ HAE ) have focused on adult patients. Many of the previous …

Regulation of the autophagic machinery in human neutrophils

…, A Chrysanthopoulou, M Speletas… - European journal of …, 2010 - Wiley Online Library
The induction of the autophagy machinery, a process for the catabolism of cytosolic proteins
and organelles, constitutes a crucial mechanism in innate immunity. However, the …

Activation of bone morphogenetic protein/Smad signaling in bronchial epithelial cells during airway inflammation

A Rosendahl, E Pardali, M Speletas… - American journal of …, 2002 - atsjournals.org
Bone morphogenetic proteins (BMPs) are pleiotropic secreted proteins, structurally related to
transforming growth factor (TGF)-β and activins. BMPs play pivotal roles in the regulation of …

[HTML][HTML] Repeated leftover serosurvey of SARS-CoV-2 IgG antibodies, Greece, march and april 2020

…, E Petinaki, V Papaevangelou, M Speletas… - …, 2020 - eurosurveillance.org
A serosurvey of IgG antibodies against severe acute respiratory coronavirus 2 (SARS-CoV-2)
was performed during March and April 2020. Among 6,586 leftover sera, 24 (0.36%) were …

Hereditary angioedema: molecular and clinical differences among European populations

M Speletas, A Szilagyi, F Psarros… - Journal of Allergy and …, 2015 - jacionline.org
(Fig 1, B). Nevertheless, CMV-specific T-cell responses were detectable by 4.5 months post-BMT
with a stimulation index of 61 and robust IFN-g, TNF-a secretion (536.5 pg/mL and 11.4 …

[HTML][HTML] Factors associated with healthcare workers'(HCWs) acceptance of COVID-19 vaccinations and indications of a role model towards population vaccinations …

…, VA Mouchtouri, K Gogosis, M Speletas… - International Journal of …, 2021 - mdpi.com
A Knowledge, Attitudes and Practices (KAP) study was conducted at the end of May 2021
engaging 1456 healthcare workers (HCWs) from 20 hospitals throughout Greece. Acceptance …