Objectives: Despite high smoking rates, few prevalence studies of COPD have been
performed in Asia. The Nippon COPD Epidemiology (NICE) Study used spirometry to measure …

Peroxynitrite, nitrogen dioxide, and other reactive nitrogen species (RNS) that are formed in
the reaction of nitric oxide (NO) with superoxide anion, and in peroxidase-dependent …

Background Inhaled corticosteroids have been used in patients with chronic obstructive
pulmonary disease (COPD), but the potential benefits of their use in triple therapy are not well …

Background Coronavirus 229E (HCoV-229E), one of the causes of the common cold,
exacerbates chronic obstructive pulmonary disease (COPD) and bronchial asthma. Long-acting …

Purpose The Continuing to Confront COPD International Patient Survey aimed to estimate
the prevalence and burden of COPD globally and to update findings from the Confronting …

The Keap1-Nrf2 system plays a central role in cytoprotection against electrophilic/oxidative
stresses. Although Cys151, Cys273, and Cys288 of Keap1 are major sensor cysteine …

Supersulphides are inorganic and organic sulphides with sulphur catenation with diverse
physiological functions. Their synthesis is mainly mediated by mitochondrial cysteinyl-tRNA …

In experimental studies, tachykinins, especially substance P (SP), cause many of the
pathophysiological features of neurogenic inflammation. It is unclear whether these peptides are …

Adult bronchial asthma is characterized by chronic airway inflammation, and presents
clinically with variable airway narrowing (wheezes and dyspnea) and cough. Long-standing …

Bronchial asthma is characterized by chronic airway inflammation, which manifests clinically
as variable airway narrowing (wheezes and dyspnea) and cough. Long-standing asthma …