Hyperreactive site in the airway tree of asthmatic patients revealed by thickening of bronchial muscles: a morphometric study

M Ebina, H Yaegashi, R Chiba… - American Review of …, 1990 - atsjournals.org
Under the assumption that the more hyperreactive the bronchial muscles are, the greater
their work hypertrophy, we analyzed the distribution of hypertrophic smooth muscles along …

Cellular hypertrophy and hyperplasia of airway smooth muscle underlying bronchial asthma

M Ebina, T Takahashi, T Chiba, M Motomiya - Am Rev Respir Dis, 1993 - atsjournals.org
In order to study whether hyperplasia or hypertrophy of cells is responsible for the thickening
of airway muscles, 3-D morphometry of airway muscle cells was performed on resin-…

An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management

…, C Carvalho, U Costabel, M Ebina… - American journal of …, 2011 - atsjournals.org
This document is an international evidence-based guideline on the diagnosis and management
of idiopathic pulmonary fibrosis, and is a collaborative effort of the American Thoracic …

Influenza virus receptors in the human airway

K Shinya, M Ebina, S Yamada, M Ono, N Kasai… - Nature, 2006 - nature.com
Although more than 100 people have been infected by H5N1 influenza A viruses, human-to-human
transmission is rare 1 . What are the molecular barriers limiting human-to-human …

Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack

T Aikawa, S Shimura, H Sasaki, M Ebina, T Takishima - Chest, 1992 - Elsevier
To examine the changes in airways in bronchial asthma (BA) during an asthma attack causing
death, we performed morphometric analysis of autopsied lungs from three outpatients …

[HTML][HTML] Mesenchymal stem cells correct inappropriate epithelial–mesenchyme relation in pulmonary fibrosis using stanniocalcin-1

…, M Kanehira, N Tode, M Kobayashi, M Ebina… - Molecular Therapy, 2015 - cell.com
Current hypotheses suggest that aberrant wound healing has a critical role in the pathogenesis
of idiopathic pulmonary fibrosis (IPF). In these hypotheses, continuous TGF-β1 secretion …

Severe acute interstitial pneumonia and gefitinib

…, M Maemondo, K Gomi, Y Tokue, Y Kimura, M Ebina… - The Lancet, 2003 - thelancet.com
Gefitinib is an oral selective inhibitor of the epidermal growth factor receptor tyrosine kinase
that is an effective treatment for patients with advanced non-small cell lung cancer who do …

Heterogeneous increase in CD34-positive alveolar capillaries in idiopathic pulmonary fibrosis

M Ebina, M Shimizukawa, N Shibata… - American journal of …, 2004 - atsjournals.org
To elucidate the apparent contradictions in vascular remodeling in the lungs of patients with
idiopathic pulmonary fibrosis, we evaluated alveolar vascularity in relation to the various …

[HTML][HTML] Arkadia amplifies TGF‐β superfamily signalling through degradation of Smad7

…, A Komuro, K Goto, M Saitoh, A Hanyu, M Ebina… - The EMBO …, 2003 - embopress.org
Arkadia was originally identified as a protein that enhances signalling activity of Nodal and
induces mammalian nodes during early embryogenesis; however, the mechanisms by which …

[HTML][HTML] Impact and predictors of acute exacerbation of interstitial lung diseases after pulmonary resection for lung cancer

…, S Teramukai, H Kondo, A Watanabe, M Ebina… - The Journal of thoracic …, 2014 - Elsevier
Objective The study objective was to examine the incidence, risk factors, and mortality rate
of acute exacerbation of interstitial lung diseases in patients with lung cancer undergoing …