Transbronchial/transesophageal bronchoscopic ultrasound-guided fine needle aspiration for mediastinal staging of non-small cell lung cancer

…, Y Kogure, M Ryuge, S Oka, R Tsuboi, M Nakahata… - 2013 - Eur Respiratory Soc
Introduction: Although combination of endobronchial ultrasound-guided transbronchial needle
aspiration (EBUS-TBNA) and transesophageal endoscopic ultrasound with bronchoscope…

[HTML][HTML] Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers

S Nakahata, T Ichikawa, P Maneesaay, Y Saito… - Nature …, 2014 - nature.com
Constitutive phosphatidylinositol 3-kinase (PI3K)-AKT activation has a causal role in adult T-cell
leukaemia-lymphoma (ATLL) and other cancers. ATLL cells do not harbour genetic …

Alteration of enhancer of polycomb 1 at 10p11. 2 is one of the genetic events leading to development of adult T‐cell leukemia/lymphoma

S Nakahata, Y Saito, M Hamasaki… - Genes …, 2009 - Wiley Online Library
Adult T‐cell leukemia/lymphoma (ATLL) is a malignant tumor caused by latent human T‐lymphotropic
virus 1 (HTLV‐1) infection. We previously identified a common breakpoint cluster …

[PDF][PDF] … , Shiho Kitaoka, 2, 6 Naohiro Egawa, 2, 5 Mayu Yamane, Ryunosuke Ikeda, Kayoko Tsukita, 2 Naoki Amano, 3 Akira Watanabe, 3 Masafumi Morimoto, 4 Jun …

T Nakahata, H Inoue, MK Saito - stem-art.com
Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by mutations of the
survival of motor neuron 1 (SMN1) gene. In the pathogenesis of SMA, pathological changes of …

[HTML][HTML] Early pathogenesis of Duchenne muscular dystrophy modelled in patient-derived human induced pluripotent stem cells

E Shoji, H Sakurai, T Nishino, T Nakahata, T Heike… - Scientific reports, 2015 - nature.com
Duchenne muscular dystrophy (DMD) is a progressive and fatal muscle degenerating
disease caused by a dystrophin deficiency. Effective suppression of the primary pathology …

[PDF][PDF] Modeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs

…, M Morimoto, J Takahashi, H Hosoi, T Nakahata… - Stem cell reports, 2015 - cell.com
Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by mutations of the
survival of motor neuron 1 (SMN1) gene. In the pathogenesis of SMA, pathological changes of …

Mislocalization of syntaxin‐1 and impaired neurite growth observed in a human iPSC model for STXBP1‐related epileptic encephalopathy

…, M Kato, H Saitsu, N Matsumoto, T Nakahata… - …, 2016 - Wiley Online Library
Syntaxin‐binding protein 1 ( STXBP 1) is essential for synaptic vesicle exocytosis. Mutations
of its encoding gene, STXBP 1, are among the most frequent genetic causes of epileptic …

Down-regulation of TCF8 is involved in the leukemogenesis of adult T-cell leukemia/lymphoma

T Hidaka, S Nakahata, K Hatakeyama… - Blood, The Journal …, 2008 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATLL) is caused by latent human T-lymphotropic virus-1 (HTLV-1)
infection. To clarify the molecular mechanism underlying leukemogenesis after viral …

Development of a complete human anti‐human transferrin receptor C antibody as a novel marker of oral dysplasia and oral cancer

K Nagai, S Nakahata, S Shimosaki, T Tamura… - Cancer …, 2014 - Wiley Online Library
Oral squamous cell carcinoma (OSCC) is the sixth most common cancer worldwide. Up to
20% of oral dysplasia cases have been suggested to undergo malignant transformation to …

Clinical characteristics of 15 children with juvenile myelomonocytic leukaemia who developed blast crisis: MDS Committee of Japanese Society of Paediatric …

…, S Kojima, M Ito, A Kikuchi, T Nakahata… - British journal of …, 2014 - Wiley Online Library
Juvenile myelomonocytic leukaemia ( JMML ) is a rare haematopoietic stem cell disease of
early childhood, which can progress to blast crisis in some children. A total of 153 children …