T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance
…, A Foryst-Ludwig, M Clemenz, M Wabitsch… - … , and vascular biology, 2008 - Am Heart Assoc
Background— Adipose tissue inflammation may play a critical role in the pathogenesis of
insulin resistance (IR). The present study examined the role of lymphocytes in adipose tissue …
insulin resistance (IR). The present study examined the role of lymphocytes in adipose tissue …
Overweight and obesity in European children: definition and diagnostic procedures, risk factors and consequences for later health outcome
M Wabitsch - European journal of pediatrics, 2000 - Springer
In this article, information on the definition of obesity in childhood and adolescence, its
differential diagnosis and its adverse health effects is provided. This information can be …
differential diagnosis and its adverse health effects is provided. This information can be …
Promoting effect of glucocorticoids on the differentiation of human adipocyte precursor cells cultured in a chemically defined medium.
H Hauner, G Entenmann, M Wabitsch… - The Journal of …, 1989 - Am Soc Clin Investig
Stromal-vascular cells obtained from adult human subcutaneous adipose tissue were cultured
in a chemically defined serum-free medium. In the presence of 0.2 nM triiodothyronine …
in a chemically defined serum-free medium. In the presence of 0.2 nM triiodothyronine …
[PDF][PDF] The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity
…, WB van den Berg, N van Rooijen, M Wabitsch… - Cell metabolism, 2010 - cell.com
Obesity-induced inflammation originating from expanding adipose tissue interferes with
insulin sensitivity. Important metabolic effects have been recently attributed to IL-1β and IL-18, …
insulin sensitivity. Important metabolic effects have been recently attributed to IL-1β and IL-18, …
Insulin and cortisol promote leptin production in cultured human fat cells
M Wabitsch, P Bo Jensen, WF Blum… - Diabetes, 1996 - Am Diabetes Assoc
The aim of this study was to investigate the regulation of leptin expression and production in
cultured human adipocytes using the model of in vitro differentiated human adipocytes. …
cultured human adipocytes using the model of in vitro differentiated human adipocytes. …
Pro-Inflammatory CD11c+CD206+ Adipose Tissue Macrophages Are Associated With Insulin Resistance in Human Obesity
OBJECTIVE Insulin resistance and other features of the metabolic syndrome have been
causally linked to adipose tissue macrophages (ATMs) in mice with diet-induced obesity. We …
causally linked to adipose tissue macrophages (ATMs) in mice with diet-induced obesity. We …
Protocol for effective differentiation of 3T3-L1 cells to adipocytes
K Zebisch, V Voigt, M Wabitsch, M Brandsch - Analytical biochemistry, 2012 - Elsevier
In this note, we present a detailed procedure for highly effective and reproducible 3T3-L1
cell differentiation. Due to their potential to differentiate from fibroblasts to adipocytes, 3T3-L1 …
cell differentiation. Due to their potential to differentiate from fibroblasts to adipocytes, 3T3-L1 …
Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation
M Wabitsch, RE Brenner, I Melzner, M Braun… - International journal of …, 2001 - nature.com
OBJECTIVE: To develop and to characterize a human preadipocyte cell strain with high
capacity for adipose differentiation serving as a model for studying human adipocyte …
capacity for adipose differentiation serving as a model for studying human adipocyte …
Type 2 diabetes mellitus in children and adolescents
T Reinehr, M Wabitsch - Prevention of type 2 diabetes, 2005 - Wiley Online Library
Until very recently, Type 2 diabetes has been thought to be a rare occurrence in children
and adolescents. However, in the mid-1990s, investigators began to observe an increasing …
and adolescents. However, in the mid-1990s, investigators began to observe an increasing …
Contribution of androgens to the gender difference in leptin production in obese children and adolescents.
M Wabitsch, WF Blum, R Muche… - The Journal of …, 1997 - Am Soc Clin Investig
Recent studies demonstrated significantly higher serum leptin concentrations in females as
compared with males, even after correction for differences in body fat mass. The aim of our …
compared with males, even after correction for differences in body fat mass. The aim of our …