User profiles for Mark McPhail

Mark JW McPhail

King's College London
Verified email at kcl.ac.uk
Cited by 16612

Acute skeletal muscle wasting in critical illness

ZA Puthucheary, J Rawal, M McPhail, B Connolly… - Jama, 2013 - jamanetwork.com
Importance Survivors of critical illness demonstrate skeletal muscle wasting with associated
functional impairment. Objective To perform a comprehensive prospective characterization …

[HTML][HTML] Effect of remdesivir vs standard care on clinical status at 11 days in patients with moderate COVID-19: a randomized clinical trial

…, C Blair, H Wang, A Gaggar, DM Brainard, MJ McPhail… - Jama, 2020 - jamanetwork.com
Importance Remdesivir demonstrated clinical benefit in a placebo-controlled trial in patients
with severe coronavirus disease 2019 (COVID-19), but its effect in patients with moderate …

EUS-guided FNA for diagnosis of solid pancreatic neoplasms: a meta-analysis

MJ Hewitt, MJW McPhail, L Possamai, A Dhar… - Gastrointestinal …, 2012 - Elsevier
BACKGROUND: Preoperative diagnosis of solid pancreatic lesions remains challenging
despite advancement in imaging technologies. EUS has the benefit of being a minimally …

Magnetic resonance imaging: principles and techniques: lessons for clinicians

…, IJ Cox, SD Taylor-Robinson, MJW McPhail - Journal of clinical and …, 2015 - Elsevier
The development of magnetic resonance imaging (MRI) for use in medical investigation has
provided a huge forward leap in the field of diagnosis, particularly with avoidance of …

Lessons from look-back in acute liver failure? A single centre experience of 3300 patients

…, A Gera, VK Audimoolam, MJW McPhail… - Journal of …, 2013 - Elsevier
BACKGROUND & AIMS: Acute liver failure (ALF) is a rapidly progressive critical illness with
high mortality. Complex intensive care unit (ICU) protocols and emergency liver …

[PDF][PDF] Source and characterization of hepatic macrophages in acetaminophen‐induced acute liver failure in humans

…, R Abeles, LA Possamai, M Bruce, M McPhail… - …, 2012 - Wiley Online Library
Acetaminophen‐induced acute liver failure (AALF) is associated with innate immunity
activation, which contributes to the severity of hepatic injury and clinical outcome. A marked

[HTML][HTML] SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care

…, A Nabeebaccus, M Fish, MJ McPhail… - Nature …, 2021 - nature.com
Prognostic characteristics inform risk stratification in intensive care unit (ICU) patients with
coronavirus disease 2019 (COVID-19). We obtained blood samples (n = 474) from …

Mitochondrial metabolic manipulation by SARS-CoV-2 in peripheral blood mononuclear cells of patients with COVID-19

S Ajaz, MJ McPhail, KK Singh, S Mujib… - … of Physiology-Cell …, 2021 - journals.physiology.org
The COVID-19 pandemic has been the primary global health issue since its outbreak in
December 2019. Patients with metabolic syndrome suffer from severe complications and a …

CD14, CD16 and HLA‐DR reliably identifies human monocytes and their subsets in the context of pathologically reduced HLA‐DR expression by CD14hi/CD16neg monocytes: Expansion of CD14hi …

D Abeles, MJ McPhail, D Sowter… - Cytometry Part …, 2012 - Wiley Online Library
Abstract Changes in monocytes and their subsets (CD14 hi /CD16 neg , CD14 hi /CD16 pos
and CD14 lo /CD16 pos ) have been described in several diseases. The combination of …

[HTML][HTML] The role of monocytes and macrophages in acute and acute-on-chronic liver failure

E Triantafyllou, KJ Woollard, MJW McPhail… - Frontiers in …, 2018 - frontiersin.org
Acute and acute-on-chronic liver failure (ALF and ACLF), though distinct clinical entities, are
considered syndromes of innate immune dysfunction. Patients with ALF and ACLF display …