User profiles for Marie-Pierre Piccinni

Marie Pierre Piccinni

Professore Associato, Universitą degli Studi di Firenze
Verified email at unifi.it
Cited by 13541

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th …

…, P Parronchi, MG Giudizi, MP Piccinni… - The Journal of …, 1993 - rupress.org
The effects exerted on the in vitro development of antigen-specific T cell lines and T cell
clones by addition or neutralization of interleukin 12 (IL-12) in lymphocyte bulk culture were …

Progesterone favors the development of human T helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in …

MP Piccinni, MG Giudizi, R Biagiotti… - … (Baltimore, Md.: 1950 …, 1995 - journals.aai.org
The effect of progesterone (P) on the cytokine production profile of Ag-specific human CD4+
T cell lines and clones was investigated. T cell lines specific for purified protein derivative or …

Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones.

…, R Manetti, C Simonelli, MP Piccinni… - … (Baltimore, Md.: 1950 …, 1992 - journals.aai.org
The effects exerted on the in vitro development of purified protein derivative (PPD)-specific
or Dermatophagoides pteronyssinus group I (Der p I)-specific T cell lines (TCL) and T cell …

Defective production of both leukemia inhibitory factor and type 2 T-helper cytokines by decidual T cells in unexplained recurrent abortions

MP Piccinni, L Beloni, C Livi, E Maggi, G Scarselli… - Nature medicine, 1998 - nature.com
Leukemia inhibitory factor is essential for embryo implantation, and a shift from type 1 T-helper
to type 2 T-helper response at the fetal–maternal interface may contribute to successful …

Allergen-and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production.

P Parronchi, D Macchia, MP Piccinni… - Proceedings of the …, 1991 - National Acad Sciences
We have established a large panel of T-cell clones (TCCs) specific for Dermatophagoides
pteronyssinus and Lolium perenne group I grass pollen allergens (total, 61) and for tetanus …

IL-4 and IFN (alpha and gamma) exert opposite regulatory effects on the development of cytolytic potential by Th1 or Th2 human T cell clones.

…, C Simonelli, S Sampognaro, MP Piccinni… - … (Baltimore, Md.: 1950 …, 1992 - journals.aai.org
The cytolytic potential of a total number of 118 CD4+ human T cell clones specific for purified
protein derivative (PPD) from Mycobacterium tuberculosis, tetanus toxoid, Lolium perenne …

Role of hormone-controlled Th1-and Th2-type cytokines in successful pregnancy

MP Piccinni, C Scaletti, E Maggi… - Journal of …, 2000 - Elsevier
Development of CD4+ helper T (Th) cells into type 1 (Th1) or type 2 (Th2) effectors, as
characterized by their opposite pattern of cytokine production, can be influenced by several factors…

Interleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma …

…, R Biagiotti, P Parronchi, MP Piccinni… - The Journal of …, 1994 - rupress.org
Interleukin 12 (IL-12) facilitates the generation of a T helper type 1 (Th1) response, with high
interferon gamma (IFN-gamma) production, while inhibiting the generation of IL-4-…

Ability of HIV to Promote a TH1 to TH0 Shift and to Replicate Preferentially in TH2 and TH0 Cells

…, A Ravina, F Annunziato, M De Carli, MP Piccinni… - Science, 1994 - science.org
Both interferon γ (IFN-γ) produced by T helper 1 (T H 1) lymphocytes and interleukin-4 (IL-4)
produced by T H 2 lymphocytes were reduced in either bulk circulating mononuclear cells or …

Progesterone during pregnancy: endocrine–immune cross talk in mammalian species and the role of stress

…, B Mulac Jericevic, MP Piccinni… - American journal of …, 2007 - Wiley Online Library
Progesterone is critical for the establishment and the maintenance of pregnancy, both by its
endocrine and immunological effects. The genomic actions of progesterone are mediated by …