To cite this article: van de Pol MA, Lutter R, Smids BS, Weersink EJM, van der Zee JS.
Synbiotics reduce allergen‐induced T‐helper 2 response and improve peak expiratory flow in …

To the Editor Asthma is an obstructive airway disease that involves chronic inflammation of
the bronchial mucosa. In asthmatics, reactive oxygen species (ROS) production is elevated …

Background Asthma is a chronic inflammatory airway disease, associated with episodes of
exacerbations. Therapy with inhaled corticosteroids ( ICS ) targets airway inflammation, …

Rationale: Eosinophils drive pathophysiology in stable and exacerbating eosinophilic asthma,
and therefore treatment is focused on the reduction of eosinophil numbers. Mepolizumab, …

Background Patients with allergic asthma have exacerbations which are frequently caused
by rhinovirus infection. The antiviral tryptophan-catabolising enzyme indoleamine 2,3-…

Asthma is characterized by allergic airway inflammation which is associated with bronchial
hyperreponsiveness and airway obstruction [1]. Recent evidence indicates that activation of …

Background Asthma exacerbations are frequently triggered by rhinovirus infections. Both
asthma and respiratory tract infection can activate haemostasis. Therefore we hypothesized …

Rationale: Limited information is available on repeatability of inflammatory parameters in
whole induced sputum samples from patients with COPD. Objectives: To study short-term and …

To cite this article: van de Pol MA, Lutter R, van Ree R, van der Zee JS. Increase in allergen‐specific
IgE and ex vivo Th2 responses after a single bronchial challenge with house dust …

A beneficial effect of long-term corticosteroid treatment in patients with COPD may be linked
to suppressing inflammation, in particular neutrophilic inflammation. Effects on neutrophilic …