[HTML][HTML] Pleiotrophin regulates microglia-mediated neuroinflammation

…, C Pérez-García, M Ferrer-Alcón, M Uribarri… - Journal of …, 2017 - Springer
Background Pleiotrophin (PTN) is a cytokine found highly upregulated in the brain in different
disorders characterized by overt neuroinflammation such as neurodegenerative diseases, …

[HTML][HTML] Quantum-dot-based suspension microarray for multiplex detection of lung cancer markers: preclinical validation and comparison with the Luminex xMAP® …

R Bilan, A Ametzazurra, K Brazhnik, S Escorza… - Scientific Reports, 2017 - nature.com
A novel suspension multiplex immunoassay for the simultaneous specific detection of lung
cancer markers in bronchoalveolar lavage fluid (BALF) clinical samples based on fluorescent …

[HTML][HTML] A new biomarker panel in bronchoalveolar lavage for an improved lung cancer diagnosis

M Uribarri, I Hormaeche, R Zalacain… - Journal of thoracic …, 2014 - Elsevier
Introduction The enormous biological complexity and high mortality rate of lung cancer
highlights the need for new global approaches for the discovery of reliable early diagnostic …

Pleiotrophin differentially regulates the rewarding and sedative effects of ethanol

…, M Ferrer‐Alcón, M Uribarri… - Journal of …, 2014 - Wiley Online Library
Pleiotrophin (PTN) is a cytokine with important roles in dopaminergic neurons. We found
that an acute ethanol (2.0 g/kg, ip) administration causes a significant up‐regulation of PTN …

[HTML][HTML] Role of RPTPβ/ζ in neuroinflammation and microglia-neuron communication

…, A Ramos, MP Ramos-Álvarez, M Uribarri… - Scientific reports, 2020 - nature.com
Pleiotrophin (PTN) is a cytokine that is upregulated in different neuroinflammatory disorders.
Using mice with transgenic PTN overexpression in the brain (Ptn-Tg), we have found a …

[PDF][PDF] Influence of MTHFR C677T polymorphism on methotrexate monotherapy discontinuation in rheumatoid arthritis patients: results from the GAPAID European …

M Uribarri, O Ruiz-Larrañaga, D Arteta… - Clin Exp …, 2015 - clinexprheumatol.org
Objective Methotrexate (MTX) is the most widely prescribed drug for rheumatoid arthritis (RA)
patients, but 45% of them discontinue therapy within two years, either due to inefficacy or …

Pleiotrophin overexpression regulates amphetamine-induced reward and striatal dopaminergic denervation without changing the expression of dopamine D1 and D2 …

…, C Pérez-García, M Ferrer-Alcón, M Uribarri… - European …, 2016 - Elsevier
It was previously shown that mice with genetic deletion of the neurotrophic factor pleiotrophin
(PTN-/-) show enhanced amphetamine neurotoxicity and impair extinction of amphetamine …

Genetic association study of systemic lupus erythematosus and disease subphenotypes in European populations

O Ruiz-Larrañaga, P Migliorini, M Uribarri, L Czirják… - Clinical …, 2016 - Springer
Epidemiological studies suggest a strong contribution of genetic factors in the pathogenesis
of systemic lupus erythematosus (SLE). In the last decades, many risk loci have been …

[PDF][PDF] Genetic variants associated with rheumatoid arthritis patients and serotypes in European populations

O Ruiz-Larrañaga, M Uribarri, MC Alcaro… - Clin. Exp …, 2016 - clinexprheumatol.org
… Otsanda Ruiz-Larrañaga, PhD María Uribarri, PhD Maria C. Alcaro, PhD Sergio Escorza-Treviño,
PhD Jokin del Amo, PhD Mikel Iriondo, PhD Carmen Manzano, PhD Paola Migliorini, MD …

Chronic cocaine use causes changes in the striatal proteome depending on the endogenous expression of pleiotrophin

…, G Herradon, M Ferrer-Alcón, M Uribarri… - Chemical research in …, 2015 - ACS Publications
The neurotrophic factor pleiotrophin (PTN) is upregulated in different brain areas after the
administration of different drugs of abuse, including psychostimulants. PTN has been shown to …