Transient cyclical methylation of promoter DNA

…, B Stride, R Métivier, M Polycarpou-Schwarz… - Nature, 2008 - nature.com
Methylation of CpG dinucleotides is generally associated with epigenetic silencing of transcription
and is maintained through cellular division 1 , 2 , 3 . Multiple CpG sequences are rare …

[HTML][HTML] Iron-dependent regulation of the divalent metal ion transporter

H Gunshin, CR Allerson, M Polycarpou-Schwarz… - FEBS letters, 2001 - Elsevier
The first step in intestinal iron absorption is mediated by the H + -coupled Fe 2+ transporter
called divalent cation transporter 1/divalent metal ion transporter 1 (DCT1/DMT1) (also …

[PDF][PDF] U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly (A) polymerase

SI Gunderson, M Polycarpou-Schwarz, IW Mattaj - Molecular cell, 1998 - cell.com
It has previously been shown in vivo that bovine papillomavirus represses its late gene
expression via a 5′ splice site sequence located upstream of the late polyadenylation signal. …

Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression

…, M Price, M Polycarpou-Schwarz… - … and cellular biology, 1992 - Taylor & Francis
A 420-bp fragment from the 5′ end of the rat thyroperoxidase (TPO) gene was fused to a
luciferase reporter and shown to direct cell-type-specific expression when transfected into rat …

The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation

M Polycarpou-Schwarz, M Groß, P Mestdagh, J Schott… - Oncogene, 2018 - nature.com
Breast cancer is a leading cause of cancer-related death in women. Small open reading
frame (sORF)-encoded proteins or microproteins constitute a new class of molecules often …

[PDF][PDF] The long noncoding RNA cancer susceptibility 9 and RNA binding protein heterogeneous nuclear ribonucleoprotein L form a complex and coregulate genes …

…, M Groß, A Goyal, M PolycarpouSchwarz… - …, 2018 - Wiley Online Library
The identification of viability‐associated long noncoding RNAs (lncRNAs) might be a
promising rationale for new therapeutic approaches in liver cancer. Here, we applied an RNA …

MIR100 host gene-encoded lncRNAs regulate cell cycle by modulating the interaction between HuR and its target mRNAs

…, RW Zealy, XL Li, M Polycarpou-Schwarz… - Nucleic acids …, 2018 - academic.oup.com
Long non-coding RNAs (lncRNAs) regulate vital biological processes, including cell proliferation,
differentiation and development. A subclass of lncRNAs is synthesized from microRNA …

The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance

…, M Polycarpou-Schwarz… - Nucleic acids …, 2017 - academic.oup.com
Little is known about the function of most non-coding RNAs (ncRNAs). The majority of long
ncRNAs (lncRNAs) is expressed at very low levels and it is a matter of intense debate …

LIMT is a novel metastasis inhibiting lnc RNA suppressed by EGF and downregulated in aggressive breast cancer

…, C Körner, M PolycarpouSchwarz… - EMBO molecular …, 2016 - embopress.org
Long noncoding RNA s (lnc RNA s) are emerging as regulators of gene expression in
pathogenesis, including cancer. Recently, lnc RNA s have been implicated in progression of …

Involvement of the carboxyl terminus of vertebrate poly (A) polymerase in U1A autoregulation and in the coupling of splicing and polyadenylation.

…, S Vagner, M Polycarpou-Schwarz… - Genes & …, 1997 - genesdev.cshlp.org
Interactions required for inhibition of poly(A) polymerase (PAP) by the U1 snRNP-specific
U1A protein, a reaction whose function is to autoregulate U1A protein production, are …