User profiles for Maria Bokarewa

Maria I. Bokarewa

University of Gothenburg
Verified email at rheuma.gu.se
Cited by 11036

Resistin, an adipokine with potent proinflammatory properties

M Bokarewa, I Nagaev, L Dahlberg, U Smith… - The Journal of …, 2005 - journals.aai.org
The adipokine resistin is suggested to be an important link between obesity and insulin
resistance. In the present study, we assessed the impact of resistin as inflammatogenic cytokine …

Staphylococcus aureus resists human defensins by production of staphylokinase, a novel bacterial evasion mechanism

T Jin, M Bokarewa, T Foster, J Mitchell… - The journal of …, 2004 - journals.aai.org
α-Defensins are peptides secreted by polymorphonuclear cells and provide antimicrobial
protection mediated by disruption of the integrity of bacterial cell walls. Staphylokinase is an …

Resistin competes with lipopolysaccharide for binding to toll‐like receptor 4

…, J Bjersing, A Shestakov, MI Bokarewa - Journal of cellular …, 2010 - Wiley Online Library
Toll‐like receptors (TLRs) are a family of cellular structures activated by recognition of
pathogen associated molecular sequences. The activation of TLRs triggers a variety of …

Staphylococcus aureus: staphylokinase

MI Bokarewa, T Jin, A Tarkowski - … journal of biochemistry & cell biology, 2006 - Elsevier
Staphylokinase is a 136 aa long bacteriophage encoded protein expressed by lysogenic
strains of Staphylococcus aureus. Present understanding of the role of staphylokinase during …

High mobility group box chromosomal protein 1, a DNA binding cytokine, induces arthritis

…, IM Jonsson, M Verdrengh, M Bokarewa… - … : Official Journal of …, 2003 - Wiley Online Library
Objective To examine the potential role of high mobility group box chromosomal protein 1 (HMGB‐1)
in the pathogenesis of arthritis. Methods Mice were injected intraarticularly with 1 …

Carbamylation-dependent activation of T cells: a novel mechanism in the pathogenesis of autoimmune arthritis

…, LE Dahlberg, SL Hazen, M Bokarewa - The Journal of …, 2010 - journals.aai.org
The posttranslational modification of proteins has the potential to generate neoepitopes that
may subsequently trigger immune responses. The carbamylation of lysine residues to form …

[HTML][HTML] Human resistin is a systemic immune-derived proinflammatory cytokine targeting both leukocytes and adipocytes

I Nagaev, M Bokarewa, A Tarkowski, U Smith - PloS one, 2006 - journals.plos.org
The characteristics of human resistin (RETN) are unclear and controversial despite intensive
adipose-focused research. Its transcriptional and functional similarity with the murine …

A unique population of IgG-expressing plasma cells lacking CD19 is enriched in human bone marrow

…, M Dürr, T Scheel, M Bokarewa… - Blood, The Journal …, 2015 - ashpublications.org
Specific serum antibodies mediating humoral immunity and autoimmunity are provided by
mature plasma cells (PC) residing in the bone marrow (BM), yet their dynamics and …

Outcomes of patients with systemic sclerosis-associated polyarthritis and myopathy treated with tocilizumab or abatacept: a EUSTAR observational study

…, P Airo, F Bartoli, G Fiori, M Bokarewa… - Annals of the …, 2013 - ard.bmj.com
Objective To evaluate the safety and effectiveness of tocilizumab and abatacept in systemic
sclerosis (SSc)-polyarthritis or SSc-myopathy. Methods 20 patients with SSc with refractory …

[HTML][HTML] Decreased levels of soluble receptor for advanced glycation end products in patients with rheumatoid arthritis indicating deficient inflammatory control

R Pullerits, M Bokarewa, L Dahlberg… - Arthritis research & …, 2005 - Springer
The receptor for advanced glycation end products (RAGE) is a member of the immunoglobulin
superfamily being expressed as a cell surface molecule and binding a variety of ligands. …