An Official ATS Clinical Practice Guideline: Interpretation of Exhaled Nitric Oxide Levels (FeNO) for Clinical Applications
…, SC Erzurum, CG Irvin, MW Leigh… - American journal of …, 2011 - atsjournals.org
Background: Measurement of fractional nitric oxide (NO) concentration in exhaled breath (Fe
NO ) is a quantitative, noninvasive, simple, and safe method of measuring airway …
NO ) is a quantitative, noninvasive, simple, and safe method of measuring airway …
Primary ciliary dyskinesia: diagnostic and phenotypic features
PG Noone, MW Leigh, A Sannuti, SL Minnix… - American journal of …, 2004 - atsjournals.org
Primary ciliary dyskinesia (PCD) is a genetic disease characterized by abnormalities in
ciliary structure/function. We hypothesized that the major clinical and biologic phenotypic …
ciliary structure/function. We hypothesized that the major clinical and biologic phenotypic …
[HTML][HTML] A controlled study of adenoviral-vector–mediated gene transfer in the nasal epithelium of patients with cystic fibrosis
…, JC Olsen, TL Noah, PC Hu, MW Leigh… - … England Journal of …, 1995 - Mass Medical Soc
Background Cystic fibrosis is a monogenic disease that deranges multiple systems of ion
transport in the airways, culminating in chronic infection and destruction of the lung. The …
transport in the airways, culminating in chronic infection and destruction of the lung. The …
European Respiratory Society guidelines for the diagnosis of primary ciliary dyskinesia
…, P Latzin, M Legendre, MW Leigh… - European …, 2017 - Eur Respiratory Soc
The diagnosis of primary ciliary dyskinesia is often confirmed with standard, albeit complex
and expensive, tests. In many cases, however, the diagnosis remains difficult despite the …
and expensive, tests. In many cases, however, the diagnosis remains difficult despite the …
[HTML][HTML] Clinical and genetic aspects of primary ciliary dyskinesia/Kartagener syndrome
MW Leigh, JE Pittman, JL Carson, TW Ferkol… - Genetics in …, 2009 - Elsevier
Primary ciliary dyskinesia is a genetically heterogeneous disorder of motile cilia. Most of the
disease-causing mutations identified to date involve the heavy (dynein axonemal heavy …
disease-causing mutations identified to date involve the heavy (dynein axonemal heavy …
Primary ciliary dyskinesia. Recent advances in diagnostics, genetics, and characterization of clinical disease
…, SD Davis, MA Zariwala, MW Leigh - American journal of …, 2013 - atsjournals.org
Primary ciliary dyskinesia (PCD) is a genetically heterogeneous recessive disorder of motile
cilia that leads to oto-sino-pulmonary diseases and organ laterality defects in approximately …
cilia that leads to oto-sino-pulmonary diseases and organ laterality defects in approximately …
Congenital heart disease and other heterotaxic defects in a large cohort of patients with primary ciliary dyskinesia
MP Kennedy, H Omran, MW Leigh, S Dell, L Morgan… - Circulation, 2007 - Am Heart Assoc
Background— Primary ciliary dyskinesia (PCD) is a recessive genetic disorder that is
characterized by sinopulmonary disease and reflects abnormal ciliary structure and function. Situs …
characterized by sinopulmonary disease and reflects abnormal ciliary structure and function. Situs …
Diagnosis, monitoring, and treatment of primary ciliary dyskinesia: PCD foundation consensus recommendations based on state of the art review
…, M Manion, MR Knowles, MW Leigh… - Pediatric …, 2016 - Wiley Online Library
Primary ciliary dyskinesia (PCD) is a genetically heterogeneous, rare lung disease resulting
in chronic oto‐sino‐pulmonary disease in both children and adults. Many physicians …
in chronic oto‐sino‐pulmonary disease in both children and adults. Many physicians …
Quantitation of inflammatory responses to bacteria in young cystic fibrosis and control patients
MS Muhlebach, PW Stewart, MW Leigh… - American journal of …, 1999 - atsjournals.org
Recent studies suggest that inflammation plays a role in the pathogenesis of lung disease
in cystic fibrosis (CF). The goal of the present study was to quantitatively compare …
in cystic fibrosis (CF). The goal of the present study was to quantitatively compare …
Diagnosis of primary ciliary dyskinesia. An official American Thoracic Society clinical practice guideline
…, E Guadagno, MR Knowles, MW Leigh… - American journal of …, 2018 - atsjournals.org
Background: This document presents the American Thoracic Society clinical practice
guidelines for the diagnosis of primary ciliary dyskinesia (PCD). Target Audience: Clinicians …
guidelines for the diagnosis of primary ciliary dyskinesia (PCD). Target Audience: Clinicians …