Introduction Hormonal receptors are of major importance in regula-tory physiological processes,
and major efforts have been dedicated to their pharmacological characterization. The …

The aim of the current study is to investigate whether homology models of G‐Protein‐Coupled
Receptors (GPCRs) that are based on bovine rhodopsin are reliable enough to be used …

A straightforward method for the synthesis of original 4,4-dialkoxy- or 4,4-diaryloxy-diaza-s-indacenes
(BODIPY) derivatives obtained by treatment of BODIPY 1 with various alcohols in …

To identify receptor functional domains underlying binding of the neurohypophysial
hormones vasopressin (AVP) and oxytocin (OT), we have constructed a three-dimensional (3D) …

It is shown that the helicity of optically active bridged biaryl molecules is the main factor
determining their high twisting power in biphenyl nematic liquid crystals. A mechanism of …

Graphics computer-generated three-dimensional models of all G-binding protein-coupled
receptors were built and analyzed. These models were defined using primary sequence …

A program combining ethnopharmacology and bioinformatic approaches has successfully
been applied on anti-inflammatory activity. (i) An ethnobotanical study allowed the …

Apelin plays a prominent role in body fluid and cardiovascular homeostasis. To explore
further upstream the role played by this peptide, nonpeptidic agonists and antagonists of the …

Polarity-sensitive fluorogenic dyes raised considerable attention because they can turn on
their fluorescence after binding to biological targets, allowing background-free imaging. …

The chemokine CXCL12 and the receptor CXCR4 play pivotal roles in normal vascular and
neuronal development, in inflammatory responses, and in infectious diseases and cancer. …