[HTML][HTML] Lung mesenchymal stem cells ameliorate elastase-induced damage in an animal model of emphysema

…, LP Ciuffreda, A Liparulo, M Sgambato… - Stem Cells …, 2018 - hindawi.com
Pulmonary emphysema is a respiratory condition characterized by alveolar destruction that
leads to airflow limitation and reduced lung function. Although with extensive research, the …

[HTML][HTML] New Role of Adult Lung c-kit+ Cells in a Mouse Model of Airway Hyperresponsiveness

…, G Esposito, M Matteis, M Sgambato… - Mediators of …, 2016 - hindawi.com
Structural changes contribute to airway hyperresponsiveness and airflow obstruction in
asthma. Emerging evidence points to the involvement of c-kit + cells in lung homeostasis, …

Nociceptin/Orphanin Fq in inflammation and remodeling of the small airways in experimental model of airway hyperresponsiveness

G Tartaglione, G Spaziano, M Sgambato… - Physiological …, 2018 - Wiley Online Library
It is widely recognized that airway inflammation and remodeling play a key role not only in
the central airway but also small airway pathology during asthma. Nociceptin/Orphanin FQ (N/ …

N/OFQ-NOP system and airways

B D'Agostino, M Sgambato, R Esposito… - The Nociceptin/Orphanin …, 2019 - Springer
Asthma is a heterogeneous chronic inflammatory disease of the airways. The most prevalent
form is atopic asthma, which is initiated by the exposure to (inhaled) allergens. Intermittent …

Intratracheal administration of bone marrow-derived mesenchymal stem cells ameliorates lung function

…, A De Angelis, E Piegari, M Matteis, M Sgambato… - 2016 - Eur Respiratory Soc
Background: The need for new options for chronic lung diseases promotes the research on
stem cells for lung repair. Bone marrow-derived mesenchymal stem cells (MSCs) can …

Alpha-1 antitrypsin (AAT) polymerization in alveolar macrophages of AAT deficient individuals and in smokers

…, E Miranda, D Biondini, G Turato, M Sgambato… - 2017 - Eur Respiratory Soc
Background: Alpha-1 antitrypsin (AAT) is a protease inhibitor whose deficiency, due to its
polymerization in liver cells, is associated with lung emphysema. Alveolar macrophages (AM) …

[PDF][PDF] Research Article New Role of Adult Lung c-kit Cells in a Mouse Model of Airway Hyperresponsiveness

…, E Piegari, G Esposito, M Matteis, M Sgambato… - stem cells, 2016 - academia.edu
Structural changes contribute to airway hyperresponsiveness and airflow obstruction in
asthma. Emerging evidence points to the involvement of c-kit+ cells in lung homeostasis, …

Leukotriene-mediated sex dimorphism in pulmonary arterial hypertensionmonocrotaline-induced rat.

…, TP Russo, A Rossi, F Roviezzo, R Filosa, M Sgambato… - 2018 - Eur Respiratory Soc
Background: The potential difference in prevalence and incidence according to gender,
suggests that females live longer than males after diagnosis of pulmonary arterial hypertension (…

Nociceptin modulates the inflammatory immune microenvironment in a conventional murine model of asthma

…, G Cirino, A Pinto, F Rossi, G Tartaglione, M Sgambato… - 2015 - Eur Respiratory Soc
Background: Nociceptin/Orphanin FQ (N/OFQ) is an endogenous heptadecapeptide that
selectively binds the NOP receptor involved in the airways hyperresponsiveness (AHR) and in …

[PDF][PDF] Nociceptin reduces the inflammatory immune microenvironment in a conventional murine model of airway hyperresponsiveness

B D'Agostino - academia.edu
This article has been accepted for publication and undergone full peer review but has not
been through the copyediting, typesett Page 1 Accepted Article This article has been accepted …