[HTML][HTML] Fecal serine protease profiling in inflammatory bowel diseases
…, N Akermi, S Soussou, M Wysocka… - Frontiers in cellular …, 2020 - frontiersin.org
Serine proteases are extensively known to play key roles in many physiological processes.
However, their dysregulation is often associated to several diseases including inflammatory …
However, their dysregulation is often associated to several diseases including inflammatory …
Substrate profiling of Zika virus NS 2B‐NS 3 protease
…, JI Rodriguez Martinez, R Grzywa, M Wysocka… - FEBS …, 2016 - Wiley Online Library
Zika virus ( ZIKV ), isolated from macaques in Uganda in 1947, was not considered to be a
dangerous human pathogen. However, this view has recently changed as ZIKV infections are …
dangerous human pathogen. However, this view has recently changed as ZIKV infections are …
[HTML][HTML] Antibiotic resistance, virulence, and phylogenetic analysis of Escherichia coli strains isolated from free-living birds in human habitats
Wild birds can be colonized by bacteria, which are often resistant to antibiotics and have
various virulence profiles. The aim of this study was to analyze antibiotic resistance …
various virulence profiles. The aim of this study was to analyze antibiotic resistance …
Sunflower trypsin inhibitor 1 as a molecular scaffold for drug discovery
This work is focused on SFTI-1, a member of the Bowman-Birk family of inhibitors. This 14
amino acid cyclic peptide exhibits several features ie compact rigidity, well-defined structure …
amino acid cyclic peptide exhibits several features ie compact rigidity, well-defined structure …
[HTML][HTML] Meta-analysis informed machine learning: Supporting cytokine storm detection during CAR-T cell Therapy
Cytokine release syndrome (CRS), also known as cytokine storm, is one of the most
consequential adverse effects of chimeric antigen receptor therapies that have shown otherwise …
consequential adverse effects of chimeric antigen receptor therapies that have shown otherwise …
[PDF][PDF] Rola lekarzy niestomatologów w zapobieganiu próchnicy wczesnego dzieciństwa
S Janus, D Olczak-Kowalczyk, M Wysocka - Nowa Pediatr, 2011 - ppm.edu.pl
Presented paper gives a definition of the early childhood caries, accompanied by epidemiological
data. it describes main rules of preventive work, including actions undertaken as early …
data. it describes main rules of preventive work, including actions undertaken as early …
[HTML][HTML] Biochemical and Structural Characterization of SplD Protease from Staphylococcus aureus
M Zdzalik, M Kalinska, M Wysocka, J Stec-Niemczyk… - PLoS …, 2013 - journals.plos.org
Staphylococcus aureus is a dangerous human pathogen. A number of the proteins secreted
by this bacterium are implicated in its virulence, but many of the components of its …
by this bacterium are implicated in its virulence, but many of the components of its …
Introduction of non-natural amino acid residues into the substrate-specific P1 position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors
A series of trypsin inhibitor SFTI-1compounds modified in substrate-specific P 1 position was
synthesized by the solid-phase method. Lys5 present in the wild inhibitor was replaced by …
synthesized by the solid-phase method. Lys5 present in the wild inhibitor was replaced by …
Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C
Cathepsin C (CatC) is a dipeptidyl-exopeptidase which activates neutrophil serine protease
precursors (elastase, proteinase 3, cathepsin G and NSP4) by removing their N-terminal …
precursors (elastase, proteinase 3, cathepsin G and NSP4) by removing their N-terminal …
Large language models, scientific knowledge and factuality: A systematic analysis in antibiotic discovery
Inferring over and extracting information from Large Language Models (LLMs) trained on a
large corpus of scientific literature can potentially drive a new era in biomedical research, …
large corpus of scientific literature can potentially drive a new era in biomedical research, …