Imaging Human Brain Perfusion with Inhaled Hyperpolarized 129Xe MR Imaging

MR Rao, NJ Stewart, PD Griffiths, G Norquay, JM Wild - Radiology, 2018 - pubs.rsna.org
Purpose To evaluate the feasibility of directly imaging perfusion of human brain tissue by
using magnetic resonance (MR) imaging with inhaled hyperpolarized xenon 129 ( 129 Xe). …

Comparison of 3He and 129Xe MRI for evaluation of lung microstructure and ventilation at 1.5T

…, FC Horn, G Norquay, M Rao… - Journal of magnetic …, 2018 - Wiley Online Library
Background To support translational lung MRI research with hyperpolarized 129 Xe gas,
comprehensive evaluation of derived quantitative lung function measures against established …

High resolution spectroscopy and chemical shift imaging of hyperpolarized 129Xe dissolved in the human brain in vivo at 1.5 tesla

M Rao, NJ Stewart, G Norquay… - Magnetic resonance …, 2016 - Wiley Online Library
Purpose Upon inhalation, xenon diffuses into the bloodstream and is transported to the brain,
where it dissolves in various compartments of the brain. Although up to five chemically …

[HTML][HTML] In vivo methods and applications of xenon-129 magnetic resonance

H Marshall, NJ Stewart, HF Chan, M Rao… - Progress in Nuclear …, 2021 - Elsevier
Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the ventilated
lung airspaces, and can be applied to quantify lung microstructure and detailed aspects …

Hyperpolarised xenon magnetic resonance spectroscopy for the longitudinal assessment of changes in gas diffusion in IPF

…, HF Chan, M Austin, LJ Smith, G Collier, M Rao… - Thorax, 2019 - thorax.bmj.com
Prognosticating idiopathic pulmonary fibrosis (IPF) is challenging, in part due to a lack of
sensitive biomarkers. A recent article in Thorax described how hyperpolarised xenon magnetic …

Comparison of MEMS switches and PIN diodes for switched dual tuned RF coils

A Maunder, M Rao, F Robb… - Magnetic resonance in …, 2018 - Wiley Online Library
Purpose To evaluate the performance of micro‐electromechanical systems (MEMS) switches
against PIN diodes for switching a dual‐tuned RF coil between 19 F and 1 H resonant …

Dissolved hyperpolarized xenon‐129 MRI in human kidneys

J Chacon‐Caldera, A Maunder, M Rao… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose To assess the feasibility of using dissolved hyperpolarized xenon‐129 ( 129 Xe)
MRI to study renal physiology in humans at 3 T. Methods Using a flexible transceiver RF coil, …

Hyperpolarized 129Xe imaging of the brain: Achievements and future challenges

Y Shepelytskyi, V Grynko, MR Rao, T Li… - Magnetic …, 2022 - Wiley Online Library
Hyperpolarized (HP) xenon‐129 ( 129 Xe) brain MRI is a promising imaging modality currently
under extensive development. HP 129 Xe is nontoxic, capable of dissolving in pulmonary …

[PDF][PDF] Assessment of brain perfusion using hyperpolarized 129Xe MRI in a subject with established stroke.

MR Rao, G Norquay, N Stewart… - Journal of Magnetic …, 2019 - eprints.whiterose.ac.uk
Recently, the possibility of directly imaging the uptake of hyperpolarized (HP) 129Xe gas in
the brain tissue of healthy normal subjects was demonstrated at the concentration achieved …

Image Phenotyping of Preterm-Born Children Using Hyperpolarized 129Xe Lung Magnetic Resonance Imaging and Multiple-Breath Washout

…, PJC Hughes, GJ Collier, M Rao… - American Journal of …, 2023 - atsjournals.org
Rationale: Preterm birth is associated with low lung function in childhood, but little is known
about the lung microstructure in childhood. Objectives: We assessed the differential …