Background Deleterious ATM alterations are found in metastatic prostate cancer (PC); PARP
inhibition has antitumour activity against this subset, but only some ATM loss PCs respond. …

Background Reliable predictive imaging markers of response to immune checkpoint
inhibitors are needed. Purpose To develop and validate a pretreatment CT-based radiomics …

In brief Reactive oxygen species are generated throughout the pre-implantation period and
are necessary for normal embryo formation. However, at pathological levels, they result in …

The detrimental consequences of obesity on female fertility are well known, but the functional
changes that occur in the ovary in response to elevated BMI are not clear. Obesity induces …

The prevalence of obesity in adults worldwide, and specifically in women of reproductive
age, is concerning given the risks to fertility posed by the increased risk of type 2 diabetes, …

Polycystic ovary syndrome (PCOS) is a common cause of female infertility. Hyperandrogenism
is both a major symptom and key diagnostic trait of PCOS; however, the direct impact of …

METHOD Based on a qualitative pre-study with 20 children between 10 and 15 years of age
in Germany, an international team developed and revised a questionnaire. The …

Simple Summary The tomato, Solanum lycopersicum L. has great importance worldwide for
its nutritional characteristics and its antioxidant content. It is cultivated in different …

Diabetes has been linked with impaired fertility but the underlying mechanisms are not well
defined. Here we use a streptozotocin-induced diabetes mouse model to investigate the …

Allocosa alticeps and Allocosa brasiliensis are two sex-role-reversed spiders. Females locate
males and initiate courtship. Copulation occurs inside male burrows and after copulation …