Rapid advances in molecular biological techniques have made it possible to study disease
pathogenesis at a genomic level. T cell receptor (TCR) gene rearrangement is an important …

Epidemiological evidence suggests that exposure to nitrogen dioxide (NO2) through the use
of unvented gas cookers in homes is associated with respiratory symptoms. Toxicological …

Asthma is a chronic inflammatory disease of the airways. Anti-inflammatory drug therapy,
primarily using corticosteroids, is now considered the first-line treatment in the management of …

Epithelial damage and airway remodeling are consistent features of bronchial asthma and
are correlated with disease chronicity, severity, and bronchial hyperreactivity. To examine the …

The Standards of Care Committee of the British Society for Allergy and Clinical Immunology
( BSACI ) and an expert panel have prepared this guidance for the management of …

Allergic rhinitis (AR) affects more than 20% of the population in the United Kingdom and
western Europe and represents a major cause of morbidity that includes interference with usual …

This guidance for the management of patients with hymenoptera venom allergy has been
prepared by the Standards of Care Committee (SOCC) of the British Society for Allergy and …

This is the first multi-centre retrospective survey from the United Kingdom to evaluate the
aetiology and diagnostic performance of tryptase in anaphylaxis during general anaesthesia (…

Background: APC 366, a selective inhibitor of mast cell tryptase, has been shown to inhibit
antigen-induced early asthmatic response (EAR), late asthmatic response (LAR), and …

Aims To perform a pharmaco-economic analysis of prescribing alternative antibiotics in patients
with a diagnostic label of ‘penicillin allergy’ and assess whether collation of information …