User profiles for ME Ward

Mary Ward

Ulster
Verified email at ulster.ac.uk
Cited by 11116

RNA transport and local translation in neurodevelopmental and neurodegenerative disease

…, J Lippincott-Schwartz, ME Ward - Nature …, 2021 - nature.com
Neurons decentralize protein synthesis from the cell body to support the active metabolism
of remote dendritic and axonal compartments. The neuronal RNA transport apparatus, …

The threat of programmed DNA damage to neuronal genome integrity and plasticity

KW Caldecott, ME Ward, A Nussenzweig - Nature Genetics, 2022 - nature.com
The neuronal genome is particularly sensitive to loss or attenuation of DNA repair, and many
neurological diseases ensue when DNA repair is impaired. It is well-established that the …

[PDF][PDF] The psychiatric cell map initiative: a convergent systems biological approach to illuminating key molecular pathways in neuropsychiatric disorders

…, L Mucke, S Finkbeiner, L Gan, N Sestan, ME Ward… - Cell, 2018 - cell.com
Although gene discovery in neuropsychiatric disorders, including autism spectrum disorder,
intellectual disability, epilepsy, schizophrenia, and Tourette disorder, has accelerated, …

The role of ISAba1 in expression of OXA carbapenemase genes in Acinetobacter baumannii

…, ME Ward, N Woodford, ME Kaufmann… - FEMS microbiology …, 2006 - academic.oup.com
ISAba1 was found in all widespread clones of Acinetobacter baumannii in the United Kingdom.
All isolates studied had a bla OXA-51-like carbapenemase gene; some also had bla OXA…

Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp.

…, MJ Ellington, JM Coelho, JF Turton, ME Ward… - International journal of …, 2006 - Elsevier
Carbapenem resistance in Acinetobacter baumannii is a growing public health concern and
is most often mediated by OXA carbapenemases. We describe a novel multiplex …

Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum β-lactamases in the UK

N Woodford, ME Ward, ME Kaufmann… - Journal of …, 2004 - academic.oup.com
Objectives: During 2003, the Health Protection Agency's Antibiotic Resistance Monitoring
and Reference Laboratory began to receive isolates of Escherichia coli for confirmation of …

How wages change: micro evidence from the International Wage Flexibility Project

…, ME Schweitzer, J Turunen, ME Ward - Journal of Economic …, 2007 - aeaweb.org
Workers' wages are not set in a spot market. Instead, the wages of most workers—at least
those who do not switch jobs—typically change only annually and are mediated by a complex …

[HTML][HTML] TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

…, T Lashley, J Ule, E Buratti, J Humphrey, ME Ward… - Nature, 2022 - nature.com
Variants of UNC13A, a critical gene for synapse function, increase the risk of amyotrophic
lateral sclerosis and frontotemporal dementia 1 , 2 – 3 , two related neurodegenerative …

The relationship between upper respiratory infections and hospital admissions for asthma: a time-trend analysis.

…, BS Robinson, SH Myint, ME Ward… - American journal of …, 1996 - atsjournals.org
We have shown that viruses are associated with 80 to 85% of asthma exacerbations in
school-age children in the community. We hypothesize that viral infections are also associated …

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons

…, A Zhang, M Coba, C Grunseich, ME Ward… - Nature medicine, 2018 - nature.com
An intronic GGGGCC repeat expansion in C9ORF72 is the most common cause of
amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), but the pathogenic …