… Sleeman provided direction and guidance. … Copyright © 2014 Camelo, Dunmore,
Sleeman and Clarke. This is an open-access article distributed under the terms of the Creative …

GM-CSF is a well-known haemopoietic growth factor that is used in the clinic to correct
neutropaenia, usually as a result of chemotherapy. GM-CSF also has many pro-inflammatory …

The chemokine CXCL 13 has a key role in secondary lymphoid tissue orchestration and
lymphoid neogenesis. Transgenic mice deficient in CXCL 13 or its receptor CXCR 5 have …

… Dr Sleeman: contributed to conception of the project design and contributed to and … Drs
Woods, May, Sleeman, and Anderson are employees of MedImmune. Dr Rugman and Ms …

In response to infections and irritants, the respiratory epithelium releases the alarmin interleukin
(IL)-33 to elicit a rapid immune response. However, little is known about the regulation …

Background Dupilumab, a fully human monoclonal antibody that binds IL‐4Rα and inhibits
signaling of both IL‐4 and IL‐13, has shown efficacy across multiple diseases with underlying …

Although radiotherapy has been used for over a century to locally control tumor growth,
alone it rarely induces an abscopal response or systemic antitumor immunity capable of …

High throughput sequencing of a mouse keratinocyte library was used to identify an expressed
sequence tag with homology to the epidermal growth factor (EGF) family of growth factors…

… Matthew A Sleeman8, … Sleeman MA … Matt Sleeman and Alex Godwood are employees
of MedImmune and own stock in AstraZeneca. Bing Wang is an employee of MedImmune. …

Innate lymphoid cells (ILCs) represent a distinct branch of the lymphoid lineage composed
of 3 major subpopulations: ILC1, ILC2, and ILC3. ILCs are mainly described as tissue-…