User profiles for M. Zignol
Matteo ZignolUnit Head, Global Tuberculosis Programme, World Health Organization Verified email at who.int Cited by 29040 |
Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis
Background Treatment outcomes for multidrug-resistant tuberculosis remain poor. We aimed
to estimate the association of treatment success and death with the use of individual drugs, …
to estimate the association of treatment success and death with the use of individual drugs, …
Epidemiology of antituberculosis drug resistance 2002–07: an updated analysis of the Global Project on Anti-Tuberculosis Drug Resistance Surveillance
A Wright, M Zignol, A Van Deun, D Falzon, SR Gerdes… - The Lancet, 2009 - thelancet.com
Background The Global Project on Anti-Tuberculosis Drug Resistance has been gathering
data since 1994. This study provides the latest data on the extent of drug resistance worldwide…
data since 1994. This study provides the latest data on the extent of drug resistance worldwide…
[HTML][HTML] Drug-resistant tuberculosis: time for visionary political leadership
…, M Zignol, D Falzon, M Raviglione… - The Lancet infectious …, 2013 - thelancet.com
… Inappropriate monotherapy and intermittent treatment are the main causes of drug resistance,
and facilitate the selection and transmission of resistant strains of M tuberculosis within …
and facilitate the selection and transmission of resistant strains of M tuberculosis within …
WHO guidelines for the programmatic management of drug-resistant tuberculosis: 2011 update
The production of guidelines for the management of drug-resistant tuberculosis (TB) fits the
mandate of the World Health Organization (WHO) to support countries in the reinforcement of …
mandate of the World Health Organization (WHO) to support countries in the reinforcement of …
Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis
Although progress has been made to reduce global incidence of drug-susceptible
tuberculosis, the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) …
tuberculosis, the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) …
Global incidence of multidrug-resistant tuberculosis
M Zignol, MS Hosseini, A Wright… - The Journal of …, 2006 - academic.oup.com
BackgroundThe global number of incident cases of multidrug-resistant (MDR) tuberculosis (TB)
in 2000 was estimated to be 272,906 (95% confidence interval [CI], 184,948–414,295). …
in 2000 was estimated to be 272,906 (95% confidence interval [CI], 184,948–414,295). …
[HTML][HTML] The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis
…, M Mihalic, M WILCOX, M ZIGNOL, M Merker… - The Lancet …, 2022 - thelancet.com
Background Molecular diagnostics are considered the most promising route to achievement
of rapid, universal drug susceptibility testing for Mycobacterium tuberculosis complex (MTBC…
of rapid, universal drug susceptibility testing for Mycobacterium tuberculosis complex (MTBC…
A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis
…, D Hanna, PS Kim, R Liwski, M Zignol… - European …, 2017 - Eur Respiratory Soc
A clear understanding of the genetic basis of antibiotic resistance in Mycobacterium tuberculosis
is required to accelerate the development of rapid drug susceptibility testing methods …
is required to accelerate the development of rapid drug susceptibility testing methods …
A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: Application to Mycobacterium tuberculosis
G Lamichhane, M Zignol, NJ Blades… - Proceedings of the …, 2003 - National Acad Sciences
We describe a postgenomic in silico approach for identifying genes that are likely to be
essential and estimate their proportion in haploid genomes. With the knowledge of all sites …
essential and estimate their proportion in haploid genomes. With the knowledge of all sites …
Rapid molecular TB diagnosis: evidence, policy making and global implementation of Xpert MTB/RIF
…, W Van Gemert, L D'Ambrosio, M Zignol… - European …, 2013 - Eur Respiratory Soc
If tuberculosis (TB) is to be eliminated as a global health problem in the foreseeable future,
improved detection of patients, earlier diagnosis and timely identification of rifampicin …
improved detection of patients, earlier diagnosis and timely identification of rifampicin …