The pharmacokinetics and pharmacodynamics of drugs are different in adult and paediatric
populations, the latter being particularly heterogeneous. These differences in …

The pharmacokinetics and pharmacodynamics of drugs are significantly altered in the burn
patient, and the burn patient population shows wide inter- and intraindividual variation in …

Diacerein is a drug for the treatment of patients with osteoarthritis. This drug is administered
orally as 50mg twice daily. Diacerein is entirely converted into rhein before reaching the …

… In addressing this question Todd uses the abundance of source … In this ground-breaking
study Margo Todd has harnessed this … The right of Margo Todd to be identified as author of this …

To explore possible mechanisms underlying hypoxia-induced pulmonary vasoconstriction,
the effect of hypoxia on outward K+ current (Iout) was evaluated in primary cultured rat …

Background Two previous studies have examined the association between an increased
posterior tibial slope and anterior cruciate ligament (ACL) injuries as measured on plain …

A dosage system expressed in terms of röntgens is proposed for the treatment of cancer of
the uterine cervix. The anatomy of the part is considered in relation to spread of disease and …

… However, the results so far obtained suggest that, when using our X-ray technique (Tod and
Meredith, 1938; Paterson, 1948) and an X-ray dose to the parametria (Point B) of 3000 r in …

… 6 weeks between cycles: CCNU (110 mg/m 2 ) administered on day 1, procarbazine (60
mg/m 2 ) administered on days 8 to 21, and vincristine (1.4 mg/m 2 , max. 2 mg) administered on …

Sorafenib, a new oral multikinase inhibitor with antiangiogenic properties, has demonstrated
preclinical and clinical activity against several tumor types. The aims of this study were to …