User profiles for M. Rådinger

Madeleine Rådinger, Professor

University of Gothenburg, Krefting Research Centre
Verified email at lungall.gu.se
Cited by 2184

Spotlight on microRNAs in allergy and asthma

…, A Rebane, S Krauss‐Etschmann, M Rådinger - Allergy, 2021 - Wiley Online Library
In past 10 years, microRNAs (miRNAs) have gained scientific attention due to their importance
in the pathophysiology of allergic diseases and their potential as biomarkers in liquid …

The multiple roles of phosphoinositide 3-kinase in mast cell biology

MS Kim, M Rådinger, AM Gilfillan - Trends in immunology, 2008 - cell.com
Mast cells play a central role in the initiation of inflammatory responses associated with asthma
and other allergic disorders. Receptor-mediated mast cell growth, differentiation, homing …

[HTML][HTML] The airway epithelium—A central player in asthma pathogenesis

J Calvén, E Ax, M Rådinger - International Journal of Molecular Sciences, 2020 - mdpi.com
Asthma is a chronic inflammatory airway disease characterized by variable airflow obstruction
in response to a wide range of exogenous stimuli. The airway epithelium is the first line of …

MicroRNA-155 is essential for TH2-mediated allergen-induced eosinophilic inflammation in the lung

…, M Sjöstrand, A Bossios, M Eldh, M Rådinger - Journal of Allergy and …, 2014 - Elsevier
Background Allergic asthma is a chronic disease of the conducting airways characterized by
T H 2 inflammation and tissue remodeling after exposure to inhaled allergens. Although the …

Generation, isolation, and maintenance of human mast cells and mast cell lines derived from peripheral blood or cord blood

M Rådinger, BM Jensen, HS Kuehn… - Current protocols in …, 2010 - Wiley Online Library
Antigen‐mediated mast cell activation is a pivotal step in the initiation of allergic disorders
including anaphylaxis and atopy. To date, studies aimed at investigating the mechanisms …

MicroRNA-155 is a critical regulator of type 2 innate lymphoid cells and IL-33 signaling in experimental models of allergic airway inflammation

…, C Malmhäll, P Ramos-Ramírez, M Rådinger - Journal of Allergy and …, 2017 - Elsevier
Background Allergic airway inflammation is triggered by allergen exposure through several
steps including release of IL-33, which promotes cytokine (IL-5, IL-13) production by type 2 …

[HTML][HTML] Mast cell exosomes promote lung adenocarcinoma cell proliferation–role of KIT-stem cell factor signaling

…, C Lässer, GV Shelke, J Wang, M Rådinger… - Cell communication and …, 2014 - Springer
Background Human cells release nano-sized vesicles called exosomes, containing mRNA,
miRNA and specific proteins. Exosomes from one cell can be taken up by another cell, which …

Effects of the antifungal imidazole ketoconazole on CYP1A and CYP3A in rainbow trout and killifish

T Hegelund, K Ottosson, M Rådinger… - … and Chemistry: An …, 2004 - Wiley Online Library
The use of N‐substituted imidazoles is widespread, and imidazole and triazole fungicides
have been detected in the aquatic environment and shown to bioaccumulate in fish. We have …

Btk-dependent Rac activation and actin rearrangement following FcεRI aggregation promotes enhanced chemotactic responses of mast cells

HS Kuehn, M Rådinger, JM Brown, K Ali… - Journal of Cell …, 2010 - journals.biologists.com
Mast cells infiltrate the sites of inflammation associated with chronic atopic disease and during
helminth and bacterial infection. This process requires receptor-mediated cell chemotaxis …

Changes in the prevalence of asthma and respiratory symptoms in western Sweden between 2008 and 2016

E Borna, BI Nwaru, A Bjerg, R Mincheva, M Rådinger… - Allergy, 2019 - Wiley Online Library
Background Asthma is a common chronic inflammatory disease of the airways, with a
noticeable increase in prevalence during the second half of the 20th century. Recent studies …