[HTML][HTML] Roles of macrophage polarization and macrophage-derived miRNAs in pulmonary fibrosis

A Kishore, M Petrek - Frontiers in immunology, 2021 - frontiersin.org
This mini-review summarizes the current evidence for the role of macrophage activation and
polarization in inflammation and immune response pertinent to interstitial lung disease, …

[HTML][HTML] Involvement of microRNAs in physiological and pathological processes in the lung

T Tomankova, M Petrek, E Kriegova - Respiratory research, 2010 - Springer
To date, at least 900 different microRNA (miRNA) genes have been discovered in the human
genome. These short, single-stranded RNA molecules originate from larger precursor …

[HTML][HTML] CAVER: a new tool to explore routes from protein clefts, pockets and cavities

M Petřek, M Otyepka, P Banáš, P Košinová, J Koča… - BMC …, 2006 - Springer
Background The main aim of this study was to develop and implement an algorithm for the
rapid, accurate and automated identification of paths leading from buried protein clefts, …

Matrix metalloproteinases and their inhibitors in chronic obstructive pulmonary disease

Z Navratilova, V Kolek, M Petrek - Archivum immunologiae et therapiae …, 2016 - Springer
Chronic obstructive pulmonary disease (COPD) is characterised by irreversible airflow limitation
associated with chronic inflammation. Matrix metalloproteinases (MMPs) are proteolytic …

[PDF][PDF] MOLE: a Voronoi diagram-based explorer of molecular channels, pores, and tunnels

M Petřek, P Košinová, J Koča, M Otyepka - Structure, 2007 - cell.com
We have developed an algorithm, "MOLE," for the rapid, fully automated location and
characterization of molecular channels, tunnels, and pores. This algorithm has been made freely …

Phenotypes of organ involvement in sarcoidosis

…, A Günther, A Weihrich, M Petrek… - European …, 2018 - Eur Respiratory Soc
Sarcoidosis is a highly variable, systemic granulomatous disease of hitherto unknown
aetiology. The GenPhenReSa (Genotype–Phenotype Relationship in Sarcoidosis) project …

Serum levels of the MCP-1 chemokine in patients with ischemic stroke and myocardial infarction

…, Z Hermanova, A Boyajyan, J Lukl, M Petrek - Mediators of …, 2005 - hindawi.com
Chemokine-driven migration of inflammatory cells has been implicated in pathogenesis of
atherosclerosis-associated conditions such as ischemic stroke and myocardial infarction. In …

Interleukin-1 gene cluster polymorphisms in sarcoidosis and idiopathic pulmonary fibrosis

…, K Lenhart, KI Welsh, RM Du Bois, M Petrek - American journal of …, 2002 - atsjournals.org
Members of the interleukin-1 (IL-1) family are implicated in the pathogenesis of sarcoidosis
and idiopathic pulmonary fibrosis (IPF). We have, therefore, performed a case–control study …

Identification of immune-relevant factors conferring sarcoidosis genetic risk

…, MC Iannuzzi, BA Rybicki, M Petrek… - American journal of …, 2015 - atsjournals.org
Rationale: Genetic variation plays a significant role in the etiology of sarcoidosis. However,
only a small fraction of its heritability has been explained so far. Objectives: To define further …

CC chemokine receptor gene polymorphisms in Czech patients with pulmonary sarcoidosis

M Petrek, J Drabek, V Kolek, J Zlamal… - American journal of …, 2000 - atsjournals.org
Genes for the chemokine receptors CCR5 and CCR2 are characterized by polymorphisms
resulting in a nonfunctional receptor expression. Ligands for CCR2 and CCR5 (chemokines …