User profiles for M. Mulè
Matthew P. MulèUniversity of Cambridge | NIH OxCam | UNC Chapel Hill MSTP Verified email at cam.ac.uk Cited by 879 |
Circulating biomarkers in pulmonary arterial hypertension: update and future direction
…, R Poscia, S Ghio, M D'Alto, P Vitulo, M Mulè… - The Journal of Heart and …, 2015 - Elsevier
Pulmonary arterial hypertension (PAH) is a complex disease with a poor prognosis. In
recent years, great advances have occurred in our understanding of the pathophysiologic …
recent years, great advances have occurred in our understanding of the pathophysiologic …
Dual antiplatelet therapy versus aspirin alone in patients undergoing transcatheter aortic valve implantation
GP Ussia, M Scarabelli, M Mulè, M Barbanti… - The American journal of …, 2011 - Elsevier
Dual antiplatelet therapy (DAPT) with clopidogrel and aspirin is a widely accepted strategy
in patients undergoing transcatheter aortic valve implantation (TAVI), but this approach is not …
in patients undergoing transcatheter aortic valve implantation (TAVI), but this approach is not …
[HTML][HTML] Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination
Several studies have shown that the pre-vaccination immune state is associated with the
antibody response to vaccination. However, the generalizability and mechanisms that underlie …
antibody response to vaccination. However, the generalizability and mechanisms that underlie …
Intravenous nanoparticle vaccination generates stem-like TCF1+ neoantigen-specific CD8+ T cells
Personalized cancer vaccines are a promising approach for inducing T cell immunity to tumor
neoantigens. Using a self-assembling nanoparticle vaccine that links neoantigen peptides …
neoantigens. Using a self-assembling nanoparticle vaccine that links neoantigen peptides …
New perspectives on management of idiopathic pulmonary fibrosis
…, R Giuliano, S Palmucci, M Mulè… - … in Chronic Disease, 2016 - journals.sagepub.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive parenchymal lung disease
characterized by a median survival of 3–5 years following diagnosis. The diagnosis is based on …
characterized by a median survival of 3–5 years following diagnosis. The diagnosis is based on …
Exercise stress echocardiography of the pulmonary circulation: limits of normal and sex differences
…, RR Vanderpool, M Mulè, MG Russo, M D'Alto… - Chest, 2012 - Elsevier
… /min/m 2 for men and 2.8 L/min/m 2 for women.24, 25 However, in these studies, body
size-corrected right ventricular volume and mass were lower in women.24, 25 The present results …
size-corrected right ventricular volume and mass were lower in women.24, 25 The present results …
Exercise stress echocardiography for the study of the pulmonary circulation
Exercise stress tests have been used for the diagnosis of pulmonary hypertension, but with
variable protocols and uncertain limits of normal. The pulmonary haemodynamic response to …
variable protocols and uncertain limits of normal. The pulmonary haemodynamic response to …
[HTML][HTML] Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses
Abstract Systems vaccinology has defined molecular signatures and mechanisms of immunity
to vaccination. However, comparative analysis of immunity to different vaccines is lacking. …
to vaccination. However, comparative analysis of immunity to different vaccines is lacking. …
Broad immune activation underlies shared set point signatures for vaccine responsiveness in healthy individuals and disease activity in patients with lupus
Responses to vaccination and to diseases vary widely across individuals, which may be
partly due to baseline immune variations. Identifying such baseline predictors of immune …
partly due to baseline immune variations. Identifying such baseline predictors of immune …
[HTML][HTML] Normalizing and denoising protein expression data from droplet-based single cell profiling
MP Mulè, AJ Martins, JS Tsang - Nature communications, 2022 - nature.com
Multimodal single-cell profiling methods that measure protein expression with oligo-conjugated
antibodies hold promise for comprehensive dissection of cellular heterogeneity, yet the …
antibodies hold promise for comprehensive dissection of cellular heterogeneity, yet the …