User profiles for M. Leeman

Michel Leeman

Syncom BV
Verified email at syncom.nl
Cited by 1630

The structure, regulation, and function of human matrix metalloproteinase-13

MF Leeman, S Curran, GI Murray - Critical reviews in biochemistry …, 2002 - Taylor & Francis
Matrix metalloproteinase-13 (MMP-13) is a proteolytic enzyme that belongs to a large family
of extracellular matrix-degrading endopeptidases that are characterized by a zinc-binding …

New insights into the roles of matrix metalloproteinases in colorectal cancer development and progression

MF Leeman, S Curran, GI Murray - The Journal of Pathology: A …, 2003 - Wiley Online Library
This review outlines new concepts that are emerging for the functions of matrix metalloproteinases
in colorectal cancer development and progression. The two main concepts that will be …

Serial lactate determinations during circulatory shock

JL VINCENT, P Dufaye, J Berré, M LEEMAN… - Critical care …, 1983 - journals.lww.com
RESULTS Before treatment of circulatory shock, lactate concen-trations averaged 80: 1, 9
mMol/L in the 9 patients who subsequently improved vs 13. 1: 1.8 mMol/L in the 8 patients for …

[PDF][PDF] Induction of systemic resistance against Fusarium wilt of radish by lipopolysaccharides of Pseudomonas fluorescens

M Leeman, JA Van Pelt, FM Den Ouden… - Phytopathology, 1995 - apsnet.org
In commercial greenhouse trials, Pseudomonas fluorescens strain WCS374 suppressed
Fusarium wilt and increased radish yield. In bioassays, the involvement of lipopolysaccharides (…

[PDF][PDF] Iron availability affects induction of systemic resistance to Fusarium wilt of radish by Pseudomonas fluorescens

M Leeman, FM Den Ouden, JA Van Pelt, FPM Dirkx… - Phytopathology, 1996 - apsnet.org
… This system is described by Leeman et al. (30). In this experimental design, the bacteria,
SA (Baker, 100 fg to 100 pg per root, pH 6.5), or purified pseudobactins (70 pg per root) were …

[PDF][PDF] Dose-response relationships in biological control of Fusarium wilt of radish by Pseudomonas spp.

JM Raaijmakers, M Leeman, MMP Van Oorschot… - Phytopathology, 1995 - apsnet.org
Leeman et al. (19) demonstrated that strain WCS358 does not induce resistance in
radish against Fusarium wilt. For the preparation of bacterial suspensions, strains were …

Emergence of a single solid chiral state from a nearly racemic amino acid derivative

…, T Izumi, A Millemaggi, M Leeman… - Journal of the …, 2008 - ACS Publications
The evolution of a single chiral solid state is reported for an amino acid derivative starting
from a nearly racemic mixture of solid left- and right-handed crystals. Attrition-enhanced …

Albumin administration improves organ function in critically ill hypoalbuminemic patients: a prospective, randomized, controlled, pilot study

…, C Melot, D De Backer, J Berre, M Leeman… - Critical care …, 2006 - journals.lww.com
Objective: To test the hypothesis that administration of albumin to correct hypoalbuminemia
might have beneficial effects on organ function in a mixed population of critically ill patients. …

Glaucoma and blood pressure

M Leeman, P Kestelyn - Hypertension, 2019 - Am Heart Assoc
The pathogenesis of glaucoma is incompletely understood, but the death of axons grouped
together at the optic disc implies that this anatomic area is primarily involved. The typical …

Erythropoietin response is blunted in critically ill patients

P Rogiers, H Zhang, M Leeman, J Nagler, H Neels… - Intensive care …, 1997 - Springer
Objectives: Critically ill patients often develop anaemia which can be related to a number of
factors. However, the exact causes of anaemia in many patients remain unexplained. We …