During the generation of a successful adaptive immune response, multiple molecular signals
are required. A primary signal is the binding of cognate antigen to an antigen receptor …

The molecular biology and clinical features of amyloid neuropathy - Benson - 2007 - Muscle
& Nerve - Wiley Online Library … Benson MD… Benson MD …

Transthyretin amyloidosis is a fatal disorder that is characterized primarily by progressive
neuropathy and cardiomyopathy. It occurs in both a mutant form (with autosomal dominant …

ClinVar ( https://www.ncbi.nlm.nih.gov/clinvar/ ) is a freely available, public archive of human
genetic variants and interpretations of their significance to disease, maintained at the …

Background Mitoxantrone-based chemotherapy palliates pain without extending survival in
men with progressive androgen-independent prostate cancer. We compared docetaxel plus …

ClinVar ( https://www.ncbi.nlm.nih.gov/clinvar/ ) at the National Center for Biotechnology
Information (NCBI) is a freely available archive for interpretations of clinical significance of …

… Kadesch for supplying the pSV2A and CAT reporter constructs and for sharing confidential
information before publication; M. Kiledjian for the plasmid pGEM3Lb147cat; H. Singh for pBS…

Background Hereditary transthyretin amyloidosis is caused by pathogenic single-nucleotide
variants in the gene encoding transthyretin (TTR) that induce transthyretin misfolding and …

For the past few years, the term ‘lifestyle migration’ has been used to refer to an increasing
number of people who take the decision to migrate based on their belief that there is a more …

The oncoprotein encoded by bc1-2 is unique because of its intracellular location (a mitochondrial
membrane protein) and apparent mode of action (suppression of apoptosis). To date, …