Transient receptor potential (TRP) channels are multifunctional signalling molecules with
many roles in sensory perception and cellular physiology. Therefore, it is not surprising that …

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Asthma and chronic obstructive pulmonary disease are inflammatory lung disorders
responsible for significant morbidity and mortality worldwide. While the importance of allergic …

BACKGROUND Cough is the most common symptom for which individuals seek medical
advice 1, 2. An acute cough is often the most prominent symptom of the common cold, which …

… Tetrodotoxin (10 6 M) completely abolished this bronchodilator … 4 M at 0.5 and 1 Hz and
virtually complete inhibition at 5 Hz (fig. 1). At a stimulation frequency of 5 Hz L-arginine (10 _3 M…

A single cytosine–guanine dinucleotide (CpG) site within coagulation factor II (thrombin)
receptor-like 3 (F2RL3) was recently found to be hypomethylated in peripheral blood genomic …

Increases in eosinophil numbers are associated with infection and allergic diseases, including
asthma, but there is also evidence that eosinophils contribute to homeostatic immune …

Background At present, nothing is known of the role of miRNAs in the immune response in
vivo despite the fact that inflammation is thought to underlie multiple acute and chronic …

… Captopril was given for 14 days, then animals were challenged with 0.25 M citric acid by
aerosol for 10 min. The response to citric acid was significantly greater in animals treated with …

In 2011, a European Respiratory Society Task Force embarked on a process to determine
the position and clinical relevance of the cough hypersensitivity syndrome, a disorder …