Over the last few decades, there has been an explosion of scientific publications reporting
the many and varied roles of transient receptor potential ( TRP ) ion channels in physiological …

Peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-activated transcription
factor belonging to the nuclear hormone receptor superfamily. PPARγ regulates several …

… Birrell's salary as well as Drs. Stevenson and Birrell's work developing models of cigarette
smoke-induced lung inflammation and lung damage at Imperial College is supported by a …

A single cytosine–guanine dinucleotide (CpG) site within coagulation factor II (thrombin)
receptor-like 3 (F2RL3) was recently found to be hypomethylated in peripheral blood genomic …

Increases in eosinophil numbers are associated with infection and allergic diseases, including
asthma, but there is also evidence that eosinophils contribute to homeostatic immune …

Background At present, nothing is known of the role of miRNAs in the immune response in
vivo despite the fact that inflammation is thought to underlie multiple acute and chronic …

Rationale: Cough is the most frequent reason for consultation with a family doctor, or with a
general or respiratory physician. Treatment options are limited and one meta-analysis …

Consumption of a naturally occurring polyphenol, resveratrol, in particular through drinking
moderate amounts of red wine, has been suggested to be beneficial to health. A plethora of …

Background Cough is the most frequent reason for consultation with a family doctor, or with
a general or respiratory physician. Treatment options are limited and a recent meta-analysis …

Cough is a common and protective reflex, but persistent coughing is debilitating and impairs
quality of life. Antitussive treatment using opioids is limited by unacceptable side effects, …