User profiles for M. A. Mall
Marcus A. MallCharité - Universitätsmedizin Berlin Verified email at charite.de Cited by 24416 |
The future of cystic fibrosis care: a global perspective
The past six decades have seen remarkable improvements in health outcomes for people
with cystic fibrosis, which was once a fatal disease of infants and young children. However, …
with cystic fibrosis, which was once a fatal disease of infants and young children. However, …
Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: lessons from mouse models
MA Mall - Journal of aerosol medicine and pulmonary drug …, 2008 - liebertpub.com
… (61) In contrast to CF patients, in whom chronic obstructive lung disease remains the ma- …
Goodman RM, Yergin BM, Landa JF, Golivanux MH, and Sackner MA: Relationship of smoking …
Goodman RM, Yergin BM, Landa JF, Golivanux MH, and Sackner MA: Relationship of smoking …
The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease
…, SY Graeber, A Dalpke, C Schultz, MA Mall - Journal of Cystic …, 2011 - Elsevier
… [24] Mall MA. Role of the amiloride-sensitive epithelial Na+ channel in the pathogenesis
and as a therapeutic target for cystic fibrosis lung disease. Exp Physiol 2009;94:171–4. …
and as a therapeutic target for cystic fibrosis lung disease. Exp Physiol 2009;94:171–4. …
[HTML][HTML] SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the rapidly
unfolding coronavirus disease 2019 (COVID-19) pandemic 1, 2. Clinical manifestations of …
unfolding coronavirus disease 2019 (COVID-19) pandemic 1, 2. Clinical manifestations of …
[HTML][HTML] Elexacaftor–tezacaftor–ivacaftor for cystic fibrosis with a single Phe508del allele
PG Middleton, MA Mall, P Dřevínek… - … England Journal of …, 2019 - Mass Medical Soc
Background Cystic fibrosis is caused by mutations in the gene encoding the cystic fibrosis
transmembrane conductance regulator (CFTR) protein, and nearly 90% of patients have at …
transmembrane conductance regulator (CFTR) protein, and nearly 90% of patients have at …
Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double …
… At week 4, treatment with elexacaftor plus tezacaftor plus ivacaftor resulted in a least squares
mean increase in body-mass index (BMI) of 0·60 kg/m 2 (95% CI 0·41 to 0·79; nominal p<0·…
mean increase in body-mass index (BMI) of 0·60 kg/m 2 (95% CI 0·41 to 0·79; nominal p<0·…
Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination
INTRODUCTION The clinical manifestations of COVID-19 vary from asymptomatic infection
to respiratory failure. Severe disease courses are primarily associated with advanced age, …
to respiratory failure. Severe disease courses are primarily associated with advanced age, …
[HTML][HTML] VX-445–tezacaftor–ivacaftor in patients with cystic fibrosis and one or two Phe508del alleles
Background VX-445 is a next-generation cystic fibrosis transmembrane conductance regulator
(CFTR) corrector designed to restore Phe508del CFTR protein function in patients with …
(CFTR) corrector designed to restore Phe508del CFTR protein function in patients with …
[HTML][HTML] Triple Therapy for Cystic Fibrosis Phe508del–Gating and –Residual Function Genotypes
PJ Barry, MA Mall, A Álvarez, C Colombo… - … England Journal of …, 2021 - Mass Medical Soc
Background Elexacaftor–tezacaftor–ivacaftor is a small-molecule cystic fibrosis transmembrane
conductance regulator (CFTR) modulator regimen shown to be efficacious in patients …
conductance regulator (CFTR) modulator regimen shown to be efficacious in patients …
[HTML][HTML] SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself
…, G Schönrich, M Raftery, T Kallinich, MA Mall… - Nature …, 2021 - nature.com
The pathogenesis of severe COVID-19 reflects an inefficient immune reaction to SARS-CoV-2.
Here we analyze, at the single cell level, plasmablasts egressed into the blood to study …
Here we analyze, at the single cell level, plasmablasts egressed into the blood to study …