Pharmacokinetics of antibiotics in the lungs

…, R Pauwels, M Van der Straeten - European Respiratory …, 1990 - Eur Respiratory Soc
This paper reviews current knowledge on the relationship between local penetration or
antibiotics and therapeutic efficacy in pulmonary and bronchial infections. The antimicrobial drug …

Capacity of the testosterone-binding globulin in human plasma and influence of specific binding of testosterone on its metabolic clearance rate

…, L Verdonck, M Van der Straeten… - The Journal of …, 1969 - academic.oup.com
The binding capacity (TeBC) and binding index (BI) of the testosterone-binding globulin (TeBG)
have been studied in several groups of patients. Before puberty, TeBC and BI are similar …

Effect of inhaled substance P and neurokinin A on the airways of normal and asthmatic subjects.

G Joos, R Pauwels, M van der Straeten - Thorax, 1987 - thorax.bmj.com
… Joos, Pauwels, van der Straeten rokinin A is a more potent bronchoconstrictor than substance
P, suggesting a predominance of SP-E receptor sites in human airways. Axon reflexes …

The effect of theophylline and enprofylline on allergen-induced bronchoconstriction

…, D Van Renterghem, M Van der Straeten… - Journal of allergy and …, 1985 - Elsevier
The effect on the allergen-induced immediate and late bronchoconstriction of theophylline
and enprofylline (3-propylxanthine), a new xanthine derivative with negligible ability to …

The effect of inhaled salmeterol on methacholine responsiveness in subjects with asthma up to 12 hours

…, RA Pauwels, MEF Van Der Straeten - Journal of allergy and …, 1992 - Elsevier
The duration of the protective effect of 50 and 100 μg of inhaled salmeterol against
methacholine-induced bronchoconstriction was compared with that of 200 μg of inhaled salbutamol …

The Effect of Endotoxin Inhalation on Airway Responsiveness and Cellular Influx in Rats1, 2

…, JC Kips, RA Peleman, ME Van Der Straeten - Am Rev Respir …, 1990 - atsjournals.org
Studies In humans suggest that airway Inflammation may modulate nonspecific airway
responsiveness. We studied In a rat model the effect of the Inhalation of endotoxin on the cellular …

IgE antibodies to bacteria in patients with bronchial asthma

R Pauwels, G Verschraegen, M Van Der Straeten - Allergy, 1980 - Wiley Online Library
… RoMAiN PAUWELS, GERDA VERSCHRAEGEN and MARCEL VAN DER STRAETEN
& Van Der Straeten, M.: Total serum IgE levels in normals and patients with chronic nonspecific …

Penetration of ampicillin and sulbactam in the lower airways during respiratory infections

…, MG Bogaert, ME Van der Straeten - Antimicrobial agents …, 1990 - Am Soc Microbiol
We studied the penetration of ampicillin-sulbactam in the alveolar lining fluid (ALF) of eight
patients after intravenous administration of 2,000 mg of ampicillin and 1,000 mg of sulbactam …

MK-571, a potent antagonist of leukotriene D4-induced bronchoconstriction in the human

…, A Buntinx, RA Pauwels, ME Van Der Straeten - Am Rev Respir …, 1991 - atsjournals.org
… LTD4 challenges were repeated during the continuous infusion, as described in Study 1,
but the highest concentration of LTD4 administered in this study was 2.4 x 10-4 M. In asthmatic …

An Animal Model for Adenosine-induced Bronchoconstriction1, 2

RA Pauwels, ME van der Straeten - Am Rev Respir Dis, 1987 - atsjournals.org
The Inhalation of adenosine Is known to cause bronchoconstrlctlon In asthmatic patients. A
thorough study of the possible role of this purine nucleoside In the pathogenesis of asthma …