This paper contains a review of the history, natural occurrence, human consumption,
metabolism, manufacture, and the results of eight standardized animal safety studies using …

… A moderate amount of IL-12 p40 mRNA (encoding IL-12 of M, 40K) was also detected in P.
acnes-… The cells were homogenized with O.5 ml of denaturing solution (4 M guanidinium …

… This cleavage was specific with a catalytic efficiency (k cat /K m , where K m is the Michaelis
constant) of 1.4 × 10 7 M −1 s −1 (K m = 0.6 ± 0.1 μM; k cat = 8.6 ± 0.3 s −1 ) (15) and was …

We have recently reported that a novel molecule, murine IFN-gamma-inducing factor (IGIF)
produced by mouse liver cells, possesses potent biologic activities, including the induction of …

The novel cytokine interferon‐γ‐inducing factor (IGIF) augments natural killer (NK) cell
activity in cultures of human peripheral blood mononuclear cells (PBMC), similarly to the …

… added 500 ml of 10 mm Tris-HCl (pH 7.2) and 1 mmMgCl 2 , and … of 10 mm Tris-HCl (pH
7.2) containing 0.3 m sucrose and 1 mm… in 600 ml of PBS containing 12 mm CHAPS, 1 mm p-…

We have previously reported the cloning of a novel cytokine, IFN-gamma-inducing factor (IGIF),
which shared some biologic activities with IL-12. In this study, we analyzed the effects of …

Background Although vascular endothelial growth factor (VEGF) is a primary mediator of
retinal angiogenesis, VEGF inhibition alone is insufficient to prevent retinal neovascularization. …

Human peripheral blood mononuclear cells (PBMC) were stimulated with three nonpathogenic
Lactobacillus strains and with one pathogenic Streptococcus pyogenes strain, and …

We have established by differential display polymerase chain reaction of mRNA that interleukin
(IL)-18 is expressed by osteoblastic stromal cells. The stromal cell populations used for …