Background and objective Idiopathic Pulmonary Fibrosis (IPF) is a progressive disease of
unknown etiology. The diagnosis is based on the identification of a pattern of usual interstitial …

Introduction Pulmonary fibrosis (PF) and its most common form, idiopathic pulmonary fibrosis
(IPF), are chronic, progressive diseases resulting in increasing loss of lung function and …

Background and objective The abnormal shortening of telomeres is a mechanism linking
ageing to idiopathic pulmonary fibrosis (IPF) that could be useful in the clinical setting. The …

Background The soluble receptor for advanced glycation end-products (sRAGE) has been
suggested that it acts as a decoy for capturing advanced glycation end-products (AGEs) and …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a rare, irreversible, and progressive
disease of the lungs. Common genetic variants, in addition to nongenetic factors, have been …

Background and objective The relationship between IPF development and environmental
factors has not been completely elucidated. Analysing geographic regions of idiopathic …

Background Non-invasive biomarkers for the assessment of disease severity in idiopathic
pulmonary fibrosis (IPF) are urgently needed. Calprotectin belongs to the S-100 proteins …

Introduction: Fibrotic interstitial lung diseases (ILDs) are the first indication for lung transplantation
(LT). Telomere dysfunction has been associated with poor post-transplant outcomes. …

Background Telomeres are nucleoprotein structures present at the terminal region of the
chromosomes. Mutations in genes coding for proteins involved in telomere maintenance are …

The therapeutic landscape for idiopathic pulmonary fibrosis (IPF) and progressive fibrosing
interstitial lung disease (PFILD) is increasingly complex, with add-on antifibrotic options now …