Autoimmune and inflammatory manifestations occur frequently in patients with primary immunodeficiencies

…, H Coignard-Biehler, L Costes, LJ Couderc… - Journal of Allergy and …, 2017 - Elsevier
Background Primary immunodeficiencies (PIDs) are inherited diseases associated with a
considerable increase in susceptibility to infections. It is known that PIDs can also predispose …

Intranasal drug delivery: an efficient and non-invasive route for systemic administration: focus on opioids

…, E Naline, C Faisy, S Blouquit-Laye, LJ Couderc… - Pharmacology & …, 2012 - Elsevier
Intranasal administration is a non-invasive route for drug delivery, which is widely used for
the local treatment of rhinitis or nasal polyposis. Since drugs can be absorbed into the …

Pneumocystis jirovecii pneumonia

…, ME Bougnoux, M Lecuit, LJ Couderc… - Infectious Disease …, 2010 - id.theclinics.com
Pneumocystis has gained attention during the last decade in the context of the AIDS epidemic
and the increasing use of cytotoxic and immunosuppressive therapies. The accumulation …

[HTML][HTML] Metabolomics of exhaled breath in critically ill COVID-19 patients: A pilot study

…, J Fleuriet, H Salvator, E Naline, LJ Couderc… - …, 2021 - thelancet.com
Background Early diagnosis of coronavirus disease 2019 (COVID-19) is of the utmost
importance but remains challenging. The objective of the current study was to characterize …

Clinical characteristics and prognostic factors of pulmonary MALT lymphoma

…, M Antoine, A Rabbat, LJ Couderc… - European …, 2009 - Eur Respiratory Soc
Mucosa-associated lymphoid tissue-derived (MALT) lymphoma, a low grade B-cell extranodal
lymphoma, is the most frequent subset of primary pulmonary lymphoma. Our objective …

A proof-of-concept, randomized, controlled trial of omalizumab in patients with severe, difficult-to-control, nonatopic asthma

…, C Taillé, G Devouassoux, F de Blay, LJ Couderc… - Chest, 2013 - Elsevier
Background While up to 50% of patients with severe asthma have no evidence of allergy,
IgE has been linked to asthma, irrespective of atopic status. Omalizumab, an anti-IgE …

Therapeutic strategy combining intravenous cyclophosphamide followed by oral azathioprine to treat worsening interstitial lung disease associated with systemic …

…, D Launay, V Le Guern, JE Kahn, LJ Couderc… - The Journal of …, 2008 - jrheum.org
Objective To evaluate the effects and safety of 6-month intravenous cyclophosphamide (CYC)
followed by 18-month oral azathioprine (AZA) therapy in patients with systemic sclerosis (…

Germline SFTPA1 mutation in familial idiopathic interstitial pneumonia and lung cancer

…, D Valeyre, LJ Couderc… - Human molecular …, 2016 - academic.oup.com
Idiopathic interstitial pneumonias (IIPs) comprise a heterogeneous group of rare lung
parenchyma disorders with high morbidity and mortality, which can occur at all ages. In adults, the …

[HTML][HTML] Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome

…, L Abel, JD Milner, B Grimbacher, LJ Couderc… - Journal of Experimental …, 2020 - rupress.org
Disclosures: Dr. Chen reported grants from Bristol-Myers Squibb during the conduct of the
study. Dr. Rosenfeld reported personal fees from Baylor Genetics Laboratories outside the …

The spectrum of malignancies in HIV‐infected patients in 2006 in France: the ONCOVIH study

…, J Cadranel, G Carcelain, LJ Couderc… - … journal of cancer, 2011 - Wiley Online Library
Since no large descriptive studies of incident cancers in HIV‐infected patients are available
in France, the nationwide cross‐sectional ONCOVIH study aimed to prospectively report new …