User profiles for Louis J Bont

Louis Bont

UMC Utrecht
Verified email at umcutrecht.nl
Cited by 19022

The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates

…, EE Walsh, RT Stein, BS Graham, LJ Bont - The Lancet Infectious …, 2018 - thelancet.com
The global burden of disease caused by respiratory syncytial virus (RSV) is increasingly
recognised, not only in infants, but also in older adults (aged ≥65 years). Advances in …

Respiratory syncytial virus hospitalization and mortality: systematic review and meta‐analysis

RT Stein, LJ Bont, H Zar, FP Polack, C Park… - Pediatric …, 2017 - Wiley Online Library
Background: Respiratory syncytial virus (RSV) is a major public health burden worldwide.
We aimed to review the current literature on the incidence and mortality of severe RSV in …

[HTML][HTML] The long-term sequelae of COVID-19: an international consensus on research priorities for patients with pre-existing and new-onset airways disease

…, PJ Barnes, J Bayry, M Bonay, LJ Bont… - The Lancet …, 2021 - thelancet.com
Persistent ill health after acute COVID-19—referred to as long COVID, the post-acute COVID-19
syndrome, or the post-COVID-19 condition—has emerged as a major concern. We …

Bivalent prefusion F vaccine in pregnancy to prevent RSV illness in infants

…, LJ Bont, T Otsuki, SL Vargas, J Gullam… - … England Journal of …, 2023 - Mass Medical Soc
Background Whether vaccination during pregnancy could reduce the burden of respiratory
syncytial virus (RSV)–associated lower respiratory tract illness in newborns and infants is …

Efficacy and safety of a bivalent RSV prefusion F vaccine in older adults

…, N Hussen, LJ Bont, J Cardona… - … England Journal of …, 2023 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) infection causes considerable illness in older
adults. The efficacy and safety of an investigational bivalent RSV prefusion F protein–based (…

Long‐term expanding human airway organoids for disease modeling

…, FE Coenjaerts, L Meyaard, LJ Bont… - The EMBO …, 2019 - embopress.org
Organoids are self‐organizing 3D structures grown from stem cells that recapitulate essential
aspects of organ structure and function. Here, we describe a method to establish long‐term…

The burden of respiratory syncytial virus in healthy term-born infants in Europe: a prospective birth cohort study

…, MA van Houten, LJ Bont, J Wildenbeest… - The Lancet …, 2023 - thelancet.com
Background Respiratory syncytial virus (RSV) is a major cause of hospitalisation in infants.
The burden of RSV infection in healthy term infants has not yet been established. Accurate …

Down syndrome: a novel risk factor for respiratory syncytial virus bronchiolitis—a prospective birth-cohort study

…, JLL Kimpen, JLM Strengers, LJ Bont - …, 2007 - publications.aap.org
OBJECTIVES. Respiratory syncytial virus is the single-most important cause of lower respiratory
tract infections in children. Preterm birth and congenital heart disease are known risk …

[HTML][HTML] Global respiratory syncytial virus-associated mortality in young children (RSV GOLD): a retrospective case series

…, H Ito, EA Goka, DE Grobbee, H Nair, LJ Bont - The Lancet Global …, 2017 - thelancet.com
Background Respiratory syncytial virus (RSV) infection is an important cause of pneumonia
mortality in young children. However, clinical data for fatal RSV infection are scarce. We …

Estimation of the timing and intensity of reemergence of respiratory syncytial virus following the COVID-19 pandemic in the US

Z Zheng, VE Pitzer, ED Shapiro, LJ Bont… - JAMA network …, 2021 - jamanetwork.com
Importance Respiratory syncytial virus (RSV) is a leading cause of hospitalizations in young
children. RSV largely disappeared in 2020 owing to precautions taken because of the …