Randomized trial of liposomal amikacin for inhalation in nontuberculous mycobacterial lung disease

…, G Eagle, JP McGinnis, L Micioni… - American journal of …, 2017 - atsjournals.org
Rationale: Lengthy, multidrug, toxic, and low-efficacy regimens limit management of pulmonary
nontuberculous mycobacterial disease. Objectives: In this phase II study, we investigated …

Case report of a patient with treatment-refractory nontuberculous mycobacteria (NTM) lung infection treated with once daily (QD) liposomal amikacin for inhalation (LAI …

D Daglian, S Lau, G Eagle, J McGinnis, L Micioni… - Chest, 2015 - journal.chestnet.org
DISCUSSION: Patients with refractory NTM lung infection have limited therapeutic options
and are often treated for lengthy durations with multidrug regimens.(1, 2) Adding LAI to this …

Amikacin (AMK) minimum inhibitory concentrations (MICs) and mutational resistance in patients with treatment-refractory nontuberculous mycobacteria (NTM) lung …

KN Olivier, G Eagle, JP McGinnis II, L Micioni… - 2015 - Eur Respiratory Soc
Aim: AMK MICs and mutational resistance were evaluated in patients with NTM-LD who
received LAI, a novel AMK formulation. Methods: In the 84-day double-blind (DB) phase, …

[CITATION][C] Efficacy of liposomal amikacin for inhalation (LAI) in achieving nontuberculous mycobacteria (NTM) culture negativity in patients whose lung infection is …

JA Biller, G Eagle, JP McGinnis, L Micioni… - D108. DIAGNOSIS …, 2015 - atsjournals.org
Objective: endpoint in patients with NTM lung infection. LAI is a novel amikacin formulation
in development for the treatment of lung infections due to NTM and(only in cystic fibrosis [CF])…

A randomized, open-label, multicenter study of liposomal amikacin for inhalation in adult patients with nontuberculous mycobacteria (NTM) lung infections caused by …

…, R Thomson, D Wagner, J Van Ingen, L Micioni… - 2015 - Eur Respiratory Soc
Mycobacterium avium: complex (MAC) lung infections are associated with significant
morbidity and mortality. Treatment of NTM lung infection is complicated by lengthy multidrug …

[CITATION][C] Analysis of functional exercise capacity (via the six-minute walk test [6MWT]) and culture negativity in patients with nontuberculous mycobacteria (NTM) …

SJ Ruoss, G Eagle, JP McGinnis, L Micioni… - D108. DIAGNOSIS …, 2015 - atsjournals.org
Analysis of Functional Exercise Capacity (Via the Six-Minute Walk Test [6MWT]) and Culture
Negativity in Patients with Nontuberculous Mycobacteria (NTM) Lung Infection Refractory to …

Optimization of the Dot Blot Protocol for the Assessment of N6-Methyladenine in Genomic DNA

MB Smith - 2019 - search.proquest.com
The dot blot is a versatile molecular biology method used to qualitatively and semi-quantitatively
assess the abundance of factors of interest in nucleic acids and proteins. After samples …

[CITATION][C] Randomized, double-blind, placebo-controlled study and open-label extension of liposomal amikacin for inhalation (LAI) in patients with recalcitrant …

KN Olivier, R Gupta, G Eagle, JPMG II, L Micioni… - Pediatr Pulmonol, 2014

[PDF][PDF] Эволюция способов введения фармакологических препаратов

МС Заволко, АВ Никифоров, АВ Наумов… - Клиническая …, 2017 - vestnik.astu.org
… McGinnis II, Liza Micioni, Keith Liu, Charles L. Daley, Kevin L. Winthrop, Stephen Ruoss,
Doreen J. …