[HTML][HTML] Epidemic and pandemic viral infections: impact on tuberculosis and the lung: A consensus by the World Association for Infectious Diseases and …

…, SN Fard, P Penttinen, L Petrone… - European …, 2020 - Eur Respiratory Soc
Major epidemics, including some that qualify as pandemics, such as severe acute
respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), HIV, influenza A (H1N1)pdm/…

Correlates of tuberculosis risk: predictive biomarkers for progression to active tuberculosis

E Petruccioli, TJ Scriba, L Petrone… - European …, 2016 - Eur Respiratory Soc
New approaches to control the spread of tuberculosis (TB) are needed, including tools to
predict development of active TB from latent TB infection (LTBI). Recent studies have described …

[HTML][HTML] A whole blood test to measure SARS-CoV-2-specific response in COVID-19 patients

L Petrone, E Petruccioli, V Vanini, G Cuzzi… - Clinical microbiology …, 2021 - Elsevier
Objectives To examine whether specific T-cell-responses to SARS-CoV-2 peptides can be
detected in COVID-19 using a whole-blood experimental setting, which may be further …

[HTML][HTML] Patients with tuberculosis have a dysfunctional circulating B-cell compartment, which normalizes following successful treatment

…, F Del Nonno, A Baiocchini, L Petrone… - PLoS …, 2016 - journals.plos.org
B-cells not only produce immunoglobulins and present antigens to T-cells, but also additional
key roles in the immune system. Current knowledge on the role of B-cells in infections …

[HTML][HTML] The definition of tuberculosis infection based on the spectrum of tuberculosis disease

GB Migliori, CWM Ong, L Petrone, L D'Ambrosio… - Breathe, 2021 - Eur Respiratory Soc
Latent tuberculosis infection was the term traditionally used to indicate tuberculosis (TB)
infection. This term was used to define “a state of persistent immune response to stimulation by …

[HTML][HTML] Immune therapy, or antiviral therapy, or both for COVID-19: a systematic review

F Cantini, D Goletti, L Petrone, S Najafi Fard, L Niccoli… - Drugs, 2020 - Springer
Background Based on current evidence, recent guidelines of the National Institute of Health,
USA indicated the use of remdesivir and dexamethasone for the treatment of COVID-19 …

[HTML][HTML] Coinfection of tuberculosis and COVID-19 limits the ability to in vitro respond to SARS-CoV-2

L Petrone, E Petruccioli, V Vanini, G Cuzzi… - International journal of …, 2021 - Elsevier
Objectives The interaction of COVID-19 and tuberculosis (TB) are still poor characterized.
Here we evaluated the immune response specific for Micobacterium tuberculosis (Mtb) and …

[HTML][HTML] Risk of tuberculosis reactivation in patients with rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis receiving non-anti-TNF-targeted biologics

F Cantini, C Nannini, L Niccoli, L Petrone… - Mediators of …, 2017 - hindawi.com
Tuberculosis (TB) still represents an important issue for public health in underdeveloped
countries, but the use of antitumor necrosis factor agents (anti-TNF) for the treatment of …

IFNγ/TNFα specific-cells and effector memory phenotype associate with active tuberculosis

E Petruccioli, L Petrone, V Vanini, A Sampaolesi… - Journal of Infection, 2013 - Elsevier
OBJECTIVES: Controversial results were reported on the role of polyfunctional T-cells in
tuberculosis (TB). Our aim was to simultaneously characterize the Mycobacterium tuberculosis (…

[HTML][HTML] The potential clinical utility of measuring severe acute respiratory syndrome coronavirus 2-specific T-cell responses

D Goletti, L Petrone, D Manissero, A Bertoletti… - Clinical Microbiology …, 2021 - Elsevier
Background Both humoral and cell-mediated responses are associated with immunity to
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although our understanding …