User profiles for LJ Palmer

Lyle John Palmer

Professor of Genetic Epidemiology, Adelaide University
Verified email at adelaide.edu.au
Cited by 74828

Population stratification and spurious allelic association

LR Cardon, LJ Palmer - The Lancet, 2003 - thelancet.com
Great efforts and expense have been expended in attempts to detect genetic polymorphisms
contributing to susceptibility to complex human disease. Concomitantly, technology for …

Genetic epidemiology and public health: hope, hype, and future prospects

GD Smith, S Ebrahim, S Lewis, AL Hansell, LJ Palmer… - The Lancet, 2005 - thelancet.com
Genetic epidemiology is a rapidly expanding research field, but the implications of findings
from such studies for individual or population health are unclear. The use of molecular …

Single nucleotide polymorphisms in innate immunity genes: abundant variation and potential role in complex human disease

R Lazarus, D Vercelli, LJ Palmer… - Immunological …, 2002 - Wiley Online Library
Under selective pressure from infectious microorganisms, multicellular organisms have evolved
immunological defense mechanisms, broadly categorized as innate or adaptive. Recent …

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

…, S Mukherjee, DR Nyholt, BA Oostra, LJ Palmer… - science, 2013 - science.org
A genome-wide association study (GWAS) of educational attainment was conducted in a
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

…, N Narisu, J O'Connell, KK Ong, BA Oostra, LJ Palmer… - Nature …, 2012 - nature.com
Recent genome-wide association studies have described many loci implicated in type 2
diabetes (T2D) pathophysiology and β-cell dysfunction but have contributed little to the …

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

…, J Hui, J Beilby, NM Warrington, A James, LJ Palmer… - Nature …, 2009 - nature.com
Eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation
of inflammatory responses and thus have important roles in the pathogenesis of …

[HTML][HTML] AI recognition of patient race in medical imaging: a modelling study

…, SC Huang, PC Kuo, MP Lungren, LJ Palmer… - The Lancet Digital …, 2022 - thelancet.com
Background Previous studies in medical imaging have shown disparate abilities of artificial
intelligence (AI) to detect a person's race, yet there is no known correlation for race on …

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

…, K Northstone, BA Oostra, M Peacock, LJ Palmer… - Nature …, 2010 - nature.com
To identify loci for age at menarche, we performed a meta-analysis of 32 genome-wide
association studies in 87,802 women of European descent, with replication in up to 14,731 …

[PDF][PDF] Genomewide scans of complex human diseases: true linkage is hard to find

J Altmüller, LJ Palmer, G Fischer, H Scherb… - The American Journal of …, 2001 - cell.com
Many "complex" human diseases, which involve multiple genetic and environmental determinants,
have increased in incidence during the past 2 decades. During the same time period, …

Genome-wide association study identifies five loci associated with lung function

…, AC Olin, K Torén, MN Cooper, AL James, LJ Palmer… - Nature …, 2010 - nature.com
Pulmonary function measures are heritable traits that predict morbidity and mortality and
define chronic obstructive pulmonary disease (COPD). We tested genome-wide association …