The discovery of the RANKL/RANK/OPG system in the mid 1990s for the regulation of bone
resorption has led to major advances in our understanding of how bone modeling and …

The discovery of the receptor activator of nuclear factor-κB ligand (RANKL)/RANK/osteoprotegerin
(OPG) system and its role in the regulation of bone resorption exemplifies how both …

Introduction Stereotactic body radiation therapy (SBRT) uses advanced technology to deliver
a potent ablative dose to deep-seated tumors in the lung, liver, spine, pancreas, kidney, …

Importance Coronavirus disease 2019 (COVID-19) is a pandemic with no specific therapeutic
agents and substantial mortality. It is critical to find new treatments. Objective To determine …

NF-κB is a family of related, dimeric transcription factors that are readily activated in cells by
signals associated with stress or pathogens. These factors are critical to host defense, as …

… = (21 + oxygen flow [in units of L/min] × 4)/100. The PaO 2 /FiO 2 ratio (in units of mm Hg)
was calculated by dividing the PaO 2 value with the FiO 2 value. A PaO 2 /FiO 2 ratio of less …

… As shown in Figure 1 f, the Fe L-edge XANES spectrum of S,N-Fe/N/C-CNT exhibits a
single peak at the L 3 -edge, which is distinctive for 3d-electrons, and no well-defined multiple …

Efforts to further elucidate structure−activity relationships (SAR) within our previously
disclosed series of β-quaternary amino acid linked l-cis-4,5-methanoprolinenitrile dipeptidyl …

We have developed a deep generative model, generative tensorial reinforcement learning (GENTRL),
for de novo small-molecule design. GENTRL optimizes synthetic feasibility, …

The molecular classification for breast carcinomas has been used in clinical studies with a
simple surrogate panel of immunohistochemistry (IHC) markers. The objective of this current …