[HTML][HTML] Lung nodules: a comprehensive review on current approach and management

K Loverdos, A Fotiadis, C Kontogianni… - Annals of thoracic …, 2019 - journals.lww.com
In daily clinical practice, radiologists and pulmonologists are faced with incidental radiographic
findings of pulmonary nodules. Deciding how to manage these findings is very important …

Can steroids reverse the severe COVID‐19 induced “cytokine storm”?

L Kolilekas, K Loverdos, S Giannakaki… - Journal of medical …, 2020 - Wiley Online Library
Severe coronavirus disease (COVID‐19) is characterized by an excessive proinflammatory
cytokine storm, resulting in acute lung injury and development of acute respiratory distress …

[HTML][HTML] Lung microbiome in asthma: current perspectives

K Loverdos, G Bellos, L Kokolatou, I Vasileiadis… - Journal of Clinical …, 2019 - mdpi.com
A growing body of evidence implicates the human microbiome as a potentially influential
player actively engaged in shaping the pathogenetic processes underlying the endotypes and …

[HTML][HTML] Fungal infections in the ICU during the COVID-19 era: descriptive and comparative analysis of 178 patients

…, N Rovina, K Tzannis, Z Sotiropoulou, K Loverdos… - Journal of Fungi, 2022 - mdpi.com
Background: COVID-19-associated fungal infections seem to be a concerning issue. The aim
of this study was to assess the incidence of fungal infections, the possible risk factors, and …

[HTML][HTML] Fungal infections in critically ill COVID-19 patients: Inevitabile malum

…, V Romanou, S Ampelioti, K Loverdos… - Journal of Clinical …, 2022 - mdpi.com
Patients with severe COVID-19 belong to a population at high risk of invasive fungal infections
(IFIs), with a reported incidence of IFIs in critically ill COVID-19 patients ranging between 5…

[HTML][HTML] The real impact of age on mortality in critically ill COVID-19 patients

…, I Ioannidou, AI Papaioannou, K Loverdos… - Journal of Personalized …, 2023 - mdpi.com
Objective: The impact of severe infection from COVID-19 and the resulting need for life
support in an ICU environment is a fact that caused immense pressure in healthcare systems …

Early COVID-19 lockdown in Greece and idiopathic pulmonary fibrosis: a beneficial “impact” beyond any expectation

…, A Bompoki, E Vasarmidi, K Loverdos… - European …, 2021 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is an irreversibly progressive diffuse lung disease
characterised by a usual interstitial pneumonia (UIP) pattern. IPF presents with an ominous …

Guanylyl cyclase activation reverses resistive breathing–induced lung injury and inflammation

C Glynos, D Toumpanakis, K Loverdos… - American journal of …, 2015 - atsjournals.org
Inspiratory resistive breathing (RB), encountered in obstructive lung diseases, induces lung
injury. The soluble guanylyl cyclase (sGC)/cyclic guanosine monophosphate (cGMP) …

Tiotropium bromide exerts anti-inflammatory effects during resistive breathing, an experimental model of severe airway obstruction

D Toumpanakis, K Loverdos, V Tzouda… - … Journal of Chronic …, 2017 - Taylor & Francis
Introduction Resistive breathing (RB), a hallmark of obstructive airway diseases, is characterized
by strenuous contractions of the inspiratory muscles that impose increased mechanical …

Inspiratory resistive breathing induces MMP-9 and MMP-12 expression in the lung

…, I Sigala, E Litsiou, K Loverdos… - … of Physiology-Lung …, 2015 - journals.physiology.org
Inspiratory resistive breathing (IRB) is characterized by large negative intrathoracic pressures
and was shown to induce pulmonary inflammation in previously healthy rats. Matrix …