Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society, …

Rationale: The Severe Asthma Research Program cohort includes subjects with persistent
asthma who have undergone detailed phenotypic characterization. Previous univariate …

Airway inflammation in severe asthma is not well characterized but may involve neutrophils.
We have compared induced sputum profiles in patients with asthma of varying severity and …

Background Air pollution from road traffic is a serious health hazard, and people with
preexisting respiratory disease may be at increased risk. We investigated the effects of short-term …

BACKGROUND: Severe asthma causes the majority of asthma morbidity. Understanding
mechanisms that contribute to the development of severe disease is important. OBJECTIVE: …

Asthma is a global health problem affecting around 300 million individuals of all ages, ethnic
groups and countries. It is estimated that around 250,000 people die prematurely each year …

Cough is a reflex action of the respiratory tract that is used to clear the upper airways. Chronic
cough lasting for more than 8 weeks is common in the community. The causes include …

Asthma is a common disease with a complex risk architecture including both genetic and
environmental factors. We performed a meta-analysis of North American genome-wide …

In China, where air pollution has become a major threat to public health, public awareness
of the detrimental effects of air pollution on respiratory health is increasing—particularly in …

Cough is one of the most common presenting symptoms of COVID-19, along with fever and
loss of taste and smell. Cough can persist for weeks or months after SARS-CoV-2 infection, …